1.03893

苯磺酸

EMPROVE^® EXPERT

• 同義詞: Benzene sulphonic acid, Benzenesulphonic acid, Besylic acid, Phenylsulfonic acid, Phenylsulphonic acid
• 線性公式: C₆H₅SO₃H
• CAS號碼: 98-11-3
• 分子量：: 158.18
• Beilstein: 742513
• EC號碼: 202-638-7
• MDL號碼: MFCD00011689
• 分類程式碼代碼: 12352005

屬性

• 生物源: synthetic
• 品質等級: 500
• 產品線: EMPROVE^® EXPERT
• 形狀: crystalline
• 技術: API processing | cocrystal formation: suitable; API processing | salt formation: suitable
• 雜質: endotoxins, low
• 應用: liquid formulation; parenterals; pharmaceutical
• SMILES 字串: OS(=O)(=O)c1ccccc1
• InChI: 1S/C6H6O3S/c7-10(8,9)6-4-2-1-3-5-6/h1-5H,(H,7,8,9)
• InChI 密鑰: SRSXLGNVWSONIS-UHFFFAOYSA-N

描述

一般說明

For protein-based therapeutics, such as monoclonal antibodies (mAbs) or plasma derived proteins, often highly concentrated protein formulations are required to meet intended dosing regimens. However, this usually comes with elevated viscosities and presents a challenge in the manufacturing process and final formulation. Our Viscosity Reduction Excipient Platform reduces the viscosity and helps overcome challenges associated with highly concentrated protein solutions.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation.
Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

應用

The Viscosity Reduction Platform is based on the combination of two new excipients, one amino acid component with one anionic component, that together can better reduce protein viscosity beyond levels achieved with single excipients. Also, combining the two components enables a balance of viscosity reduction and protein stabilization. Benzenesulfonic Acid Emprove^® Expert is part of this new proprietary technology platform.

包裝

1038930500 / 500g / Glass bottle
1038931000 / 1kg / Glass bottle

法律資訊

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS05,GHS07
• 訊號詞: Danger
• 危險聲明: H302,H314
• 防範說明: P260 - P270 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B
• 儲存類別代碼: 8A - Combustible corrosive hazardous materials
• 水污染物質分類（WGK）: WGK 1