1.02839

L-半胱氨酸 盐酸盐 一水合物

for biochemistry

• 同義詞: Cys, L-Cysteinium Chloride Monohydrate, L-Cysteine Hydrochloride, Monohydrate
• 線性公式: HSCH₂CH(NH₂)COOH · HCl · H₂O
• CAS號碼: 7048-04-6
• 分子量：: 175.63
• Beilstein: 5158059
• MDL號碼: MFCD00065606
• 分類程式碼代碼: 12352209
• 酶委員會索引編號: 200-157-7
• NACRES: NA.21

屬性

• 蒸汽壓力: <0.1 hPa ( 20 °C)
• 品質等級: 100
• 化驗: 98.5-101.0% dry basis (alkalimetric)
• 形狀: crystalline powder
• pH值: 0.8-1.2 (20 °C, 100 g/L in H₂O)
• mp: 168-170 °C
• 溶解度: 650 g/L
• 密度: 1.54 g/cm³
• 體積密度: 780 kg/m³
• 負離子痕跡: sulfate (SO₄^2-): ≤300 ppm
• 正離子痕跡: Fe: ≤20 ppm; heavy metals (as Pb): ≤10 ppm
• 儲存溫度: 2-30°C
• SMILES 字串: O.Cl.N[C@@H](CS)C(O)=O
• InChI: 1S/C3H7NO2S.ClH.H2O/c4-2(1-7)3(5)6;;/h2,7H,1,4H2,(H,5,6);1H;1H2/t2-;;/m0../s1
• InChI 密鑰: QIJRTFXNRTXDIP-JIZZDEOASA-N

描述

應用

• Smartphone-based Ellman′s colourimetric methods for the analysis of d-penicillamine formulation and thiolated polymer: Demonstrates the application of L-Cysteine hydrochloride monohydrate in developing colorimetric assays for pharmaceutical analysis, enhancing the accessibility and cost-effectiveness of drug quality control (Phadungcharoen et al., 2019).


• The effects of the thiolation with thioglycolic acid and l-cysteine on the mucoadhesion properties of the starch-graft-poly(acrylic acid): Focuses on the modification of polymers with L-Cysteine hydrochloride monohydrate to improve their mucoadhesive properties, which is critical for developing more effective drug delivery systems (Gök et al., 2017).


• On-line pre-reduction of pentavalent arsenicals by thioglycolic acid for speciation analysis by selective hydride generation-cryotrapping-atomic absorption spectrometry: Utilizes L-Cysteine hydrochloride monohydrate in analytical chemistry techniques to improve the detection and measurement of toxic elements in environmental samples, crucial for monitoring and ensuring public health (Musil et al., 2008).

生化／生理作用

NMDA谷氨酸能受体拮抗剂。

分析報告

Assay (alkalimetric, calculated on dried substance): 98.5 - 101.0 %
Identity (IR-spectrum): passes test
Identity (Chloride): passes test
Appearance: white or almost white, crystalline powder or colorless crystals
Appearance of solution (25 g/l, water): clear and not more intense in color than reference solution BY6
Spec. rotation (α 20/D, 80 g/l, hydrochloric acid 250 g/l, calc. on dried substance): +5.5 to +7.0
Spec. rotation (α 25/D, 80 g/l, hydrochloric acid 6 mol/l, calc. on dried substance): +5.7 to +6.8
Sulfate (SO₄): ≤ 300 ppm
Heavy metals (as Pb): ≤ 10 ppm
Fe (Iron): ≤ 20 ppm
Related Compounds, total (TLC): ≤ 0.5 %
Ninhydrin-positive substances (LC)(impurity A (570 nm)): ≤ 0.5 %
Ninhydrin-positive substances (LC)(any ninhydrin-positive impurity): ≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm)): ≤ 0.02 %
Ninhydrin-positive substances (LC)(total impurities): ≤ 1.0 %
Residual solvents (ICH Q3C): excluded by manufacturing process
Sulfated ash (600 °C): ≤ 0.1 %
Loss on drying (Vacuum < 0.7 kPa, P₂O₅, 24 h): 8.0 - 12.0 %
Bacterial endotoxins: ≤ 6.0 I.U./g

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable