09-827

Anti-HDAC11 Antibody

from rabbit, purified by affinity chromatography

• 同義詞: histone deacetylase 11
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human, mouse, rat
• 技術: western blot: suitable
• NCBI登錄號: NP_079103.2
• UniProt登錄號: Q96DB2
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... HDAC11(79885) ; mouse ... Hdac11(232232) ; rat ... Hdac11(297453)

描述

一般說明

HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation is a marker for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.

特異性

This antibody recognizes HDAC11.

免疫原

Epitope: Amino Acid: 228-246

Linear Peptide corresponding to human HDAC11 at amino acids 228-246.

應用

Anti-HDAC11 Antibody is a Rabbit Polyclonal Antibody for detection of HDAC11 also known as histone deacetylase 11 & has been validated in WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histone Modifying Proteins

Cell Cycle, DNA Replication & Repair

Western Blot (SNAP ID) Analysis: 0.5 µg/ml from a representative lot detected HDAC11 on 10 µg of human brain tissue lysate.

品質

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.05 µg/ml of this antibody detected HDAC11 on 10 µg of human brain tissue lysate.

標靶描述

39 kDa

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Human brain tissue lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable