07-442-AF488

Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor^™ 488 Conjugate

0.5 mg/mL, from rabbit

• 同義詞: Histone H3.1t, H3/t, H3t, H3/g
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 共軛: ALEXA FLUOR^™ 488
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: human
• 物種活性（以同源性預測）: chicken (based on 100% sequence homology), rat (based on 100% sequence homology), mouse (based on 100% sequence homology)
• 濃度: 0.5 mg/mL
• 技術: immunocytochemistry: suitable
• NCBI登錄號: NM_003493
• UniProt登錄號: Q16695
• 運輸包裝: wet ice
• 目標翻譯後修改: trimethylation (Lys9)
• 基因資訊: human ... H3C1(8350) ; mouse ... H3C1(360198) ; rat ... H3C1(679994)

描述

一般說明

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-442.

免疫原

Linear peptide corresponding to Histone H3 trimethylated at Lys9.

應用

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

This Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor^™ 488 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9).

品質

Evaluated by Immunocytochemistry in HeLa cell lysate.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected trimethyl Histone H3 (Lys9) in HeLa cells.

Alexa Fluor^™ is a registered trademark of Life Technologies.

標靶描述

~17 kDa observed (Refer to Cat. No. 07-442)

外觀

Protein A purified

Purified rabbit conjugate in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

法律資訊

ALEXA FLUOR is a trademark of Life Technologies

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable