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Key Documents

07-326

Sigma-Aldrich

抗磷酸化丝切蛋白2(Ser3)抗体

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, chicken, human

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

phosphorylation (pSer3)

基因資訊

human ... CFL2(1073)

特異性

磷酸-Cofilin 2

免疫原

对应于人磷酸-Cofilin 2氨基酸1-10(MA[pS]GVTVNDE-C)的肽

應用

抗磷酸-Cofilin 2(Ser3)抗体可检测磷酸化-Cofilin 2(Ser3)水平,已发布,经验证可用于WB。
研究子类别
细胞骨架
研究类别
细胞结构

品質

已通过免疫印迹对L6细胞(已用LIM激酶处理)的RIPA裂解液进行了常规评估

標靶描述

21kDa

外觀

0.1M Tris-甘氨酸,pH 7.4,0.15M NaCl,0.05%叠氮化钠,然后添加甘油至30%
形式:纯化
蛋白A层析

儲存和穩定性

在-20°C下可保存2年

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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C Thirion et al.
European journal of biochemistry, 268(12), 3473-3482 (2001-06-26)
Cofilins are actin binding proteins and regulate actin assembly in vivo. Numerous cofilin homologues have been characterized in various organisms including mammals. In mice, a ubiquitously expressed cofilin (CFL1) and a skeletal muscle specific cofilin (CFL2) have been described. In
J Craig Hunter et al.
Journal of molecular and cellular cardiology, 47(6), 810-818 (2009-10-06)
Although nitric oxide (NO) has received extensive attention as an anti-hypertrophic agent the mechanisms underlying its regulation of endothelin-1 (ET-1) have not been fully elucidated. Since RhoA has been identified as an important mediator of cardiac hypertrophy and is inhibited
Differential dependence of stretch and shear stress signaling on caveolin-1 in the vascular wall.
Albinsson, S; Nordstrom, I; Sward, K; Hellstrand, P
American Journal of Physiology. Cell Physiology null
Toru Amano et al.
The Journal of biological chemistry, 277(24), 22093-22102 (2002-04-02)
Actin filament dynamics play a critical role in mitosis and cytokinesis. LIM motif-containing protein kinase 1 (LIMK1) regulates actin reorganization by phosphorylating and inactivating cofilin, an actin-depolymerizing and -severing protein. To examine the role of LIMK1 and cofilin during the
Mardjaneh Sadegh Karbalaei et al.
European journal of pharmacology, 689(1-3), 179-185 (2012-05-31)
Caveolae are membrane invaginations present in a variety of cell types. Formation of caveolae depends on caveolins and on the more recently discovered family of proteins known as the cavins. Genetic ablation of caveolin-1 was previously shown to give rise

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