07-1352

Anti-acetyl STAT5B (Lys701) Antibody

from rabbit, purified by affinity chromatography

• 同義詞: Signal transducer and activator of transcription 5B
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 純化經由: affinity chromatography
• 物種活性: human
• 技術: dot blot: suitable; western blot: suitable
• NCBI登錄號: NP_036580
• UniProt登錄號: P51692
• 運輸包裝: wet ice
• 目標翻譯後修改: acetylation (Lys701)
• 基因資訊: human ... STAT5B(6777)

描述

一般說明

STAT5B (signal transducers and activators of transcription 5b) controls the expression of early response genes and takes part in cytokine signaling. Studies have linked this protein to the inhibition of NFkappaB-mediated signaling. Additional studies have shown an association of STAT5B with regulation of lactation and growth, performance, and control of adipocyte function. Constitutively active STAT5B expression is often observed in a large number of leukemia’s and solid tumors.

特異性

Other homologies: Rat and Mouse (91% sequence homology).

This antibody recognizes STAT5B acetylated at Lys701.

免疫原

Epitope: Acetylated Lys701

KLH-conjugated linear peptide corresponding to human STAT5B acetylated at Lys701.

應用

Detect acetyl STAT5B (Lys701) using this Anti-acetyl STAT5B (Lys701) Antibody validated for use in DB & WB.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

Western Blot Analysis: A representative lot was used by an independent laboratory in WB. (Ma, L., et al. (2010). Proc Natl Acad Sci U S A. 107(45):19314-19319.)

品質

Evaluated by Dot Blot in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

Dot Blot Analysis: 1 µg/mL of this antibody detected STAT5B in modified and non modified peptides of acetylated and non-acetylated STAT5B protein.

標靶描述

90 kDa calculated

外觀

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

分析報告

Control
Modified and non modified peptides of acetylated and non-acetylated STAT5B protein

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable