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重要文件

06-926

Sigma-Aldrich

Anti-p70 S6 Kinase (S6K) Antibody

Upstate®, from rabbit

同義詞:

RPS6KB1, PS6K, S6K, S6K1, STK14A, p70(S6K)-alpha, p70-S6K, p70-alpha, ribosomal protein S6 kinase, 70kDa

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
polyclonal
application:
WB
物種活性:
rat, human, mouse
技術:
western blot: suitable
citations:
6

生物源

rabbit

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, human, mouse

製造商/商標名

Upstate®

技術

western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... POTEM(641455)

特異性

p70 S6 kinase

免疫原

peptide (C-FPMISKRPEHLRMNL) corresponding to residues 511-525 of rat S6 kinase

應用

Anti-p70 S6 Kinase (S6K) Antibody detects level of p70 S6 Kinase (S6K) & has been published & validated for use in WB.
Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling

品質

routinely evaluated by immunoblot on RIPA lysates from mouse 3T3 cells

標靶描述

64kDa

外觀

Protein A chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the additional of glycerol to 30%
Format: Purified

儲存和穩定性

2 years at -20°C

分析報告

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Activation of an S6 kinase from human placenta by autophosphorylation.
Dennis, P B and Masaracchia, R A
The Journal of Biological Chemistry, 268, 19833-19841 (1993)
SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.
Cohet, N; Stewart, KM; Mudhasani, R; Asirvatham, AJ; Mallappa, C; Imbalzano, KM; Weaver et al.
Journal of Cellular Physiology null
D Chen et al.
Molecular and cellular biology, 19(7), 4684-4694 (1999-06-22)
We have previously reported that insulin and osmotic shock stimulate an increase in glucose transport activity and translocation of the insulin-responsive glucose transporter isoform GLUT4 to the plasma membrane through distinct pathways in 3T3L1 adipocytes (D. Chen, J. S. Elmendorf
Tingting Sun et al.
Aging, 12(23), 24208-24218 (2020-11-24)
The 5-year survival rate of ovarian cancer patients is only 47%, and developing novel drugs for ovarian cancer is needed. Herein, we evaluated if and how SRT2183, a sirtuin-1 activator, impairs the ovarian cancer cells. OVCAR-3 and A2780 cells were

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