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重要文件

06-315

Sigma-Aldrich

Anti-KA2/GRIK5 (Kainate Receptor) Antibody

Upstate®, from rabbit

同義詞:

Anti-EAA2, Anti-GRIK2, Anti-GluK5, Anti-KA2

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41
無性繁殖:
polyclonal
application:
ICC
IHC
IP
WB
物種活性:
rat, rabbit
技術:
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
citations:
21

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

rat, rabbit

製造商/商標名

Upstate®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... GRIK5(2901)

特異性

KA2

免疫原

21 residue synthetic peptide (KTSPPRPRPGPTGPRELTEHE) corresponding to the c-terminus of rat KA2 with a lysine added to the n-terminus

應用

Anti-KA2/GRIK5 (Kainate Receptor) Antibody is an antibody against KA2/GRIK5 (Kainate Receptor) for use in IC, IH, IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurochemistry & Neurotrophins

Neurodegenerative Diseases

品質

routinely evaluated by immunoblot on rat brain microsomal preparation

標靶描述

123kDa

外觀

Protein G Chromatography
Format: Purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

儲存和穩定性

2 years at -20°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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E P Garcia et al.
Neuron, 21(4), 727-739 (1998-11-10)
The mechanism of kainate receptor targeting and clustering is still unresolved. Here, we demonstrate that members of the SAP90/PSD-95 family colocalize and associate with kainate receptors. SAP90 and SAP102 coimmunoprecipitate with both KA2 and GluR6, but only SAP97 coimmunoprecipitates with
S Mehta et al.
The Journal of biological chemistry, 276(19), 16092-16099 (2001-03-30)
Recent studies have demonstrated that kainate receptors are associated with members of the SAP90/PSD-95 family (synapse-associated proteins (SAPs)) in neurons and that SAP90 can cluster and modify the electrophysiological properties of GluR6/KA2 kainate receptors when co-expressed in transfected cells. In
Functional cooperation between KA2 and GluR6 subunits is involved in the ischemic brain injury.
Hai-Xia Jiang, Qiu-Hua Guan, Dong-Sheng Pei, Guang-Yi Zhang
Journal of Neuroscience Research null
Role of NMDA and non-NMDA ionotropic glutamate receptors in traumatic spinal cord axonal injury
Agrawal, S. K. and Fehlings, M. G.
The Journal of Neuroscience, 17, 1055-1063 (1997)
Synaptic expression of the high-affinity kainate receptor subunit KA2 in hippocampal cultures
Roche, K. W. and Huganir, R. L.
Neuroscience, 69, 383-393 (1995)

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