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Key Documents

06-236

Sigma-Aldrich

Anti-Giα1/2 Antibody

Upstate®, from rabbit

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

mouse, human, rat, bovine

製造商/商標名

Upstate®

技術

immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... GNAI1(2770)

特異性

Recognizes Giα1 and Giα2.

免疫原

10 residue synthetic peptide (KNNLKDCGLF) corresponding to the c-terminus of Gia1 and Gia2

應用

Detect Giα1/2 using this Anti-Giα1/2 Antibody validated for use in IC, IP & WB.
Research Category
Signaling
Research Sub Category
GPCR, cAMP/cGMP & Calcium Signaling

品質

routinely evaluated by immunoblot on Rat Brain Microsomal Preparation or solubilized plasma membranes from mouse 3T3/A31 fibroblasts

標靶描述

40 kDa

外觀

A diluted rabbit serum in PBS (50 mM KHPO4, 140 mM NaCl). Frozen solution
Format: Purified

儲存和穩定性

Maintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

分析報告

Control
Widely expressed

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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J M Sands et al.
The Journal of clinical investigation, 99(6), 1399-1405 (1997-03-15)
During antidiuresis, increases in vasopressin (AVP)-elicited osmotic water permeability in the terminal inner medullary collecting duct (tIMCD) raise luminal calcium concentrations to levels (> or = 5 mM) above those associated with the formation of calcium-containing precipitates in the urine.
Disulfide bonds in the extracellular calcium-polyvalent cation-sensing receptor correlate with dimer formation and its response to divalent cations in vitro
Ward, D. T., et al
The Journal of Biological Chemistry, 273, 14476-14483 (1998)
P Barrett et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 14(11), 1619-1628 (2000-08-06)
Mimicking short photoperiod melatonin signals (16 h exposure) on primary cell cultures of melatonin target cells of the ovine pars tuberalis (PT) results in an enhanced cAMP response to forskolin stimulation relative to untreated cells, a phenomenon termed sensitization. The
Jian Shi et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 30(2), 702-715 (2015-10-16)
Depletion of sarcoplasmic reticulum (SR) Ca(2+) stores activates store-operated channels (SOCs) composed of canonical transient receptor potential (TRPC) 1 proteins in vascular smooth muscle cells (VSMCs), which contribute to important cellular functions. We have previously shown that PKC is obligatory
Rachna Kaushik et al.
Molecular biology of the cell, 14(8), 3144-3155 (2003-08-20)
Mammalian LGN/AGS3 proteins and their Drosophila Pins orthologue are cytoplasmic regulators of G-protein signaling. In Drosophila, Pins localizes to the lateral cortex of polarized epithelial cells and to the apical cortex of neuroblasts where it plays important roles in their

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