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Merck
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重要文件

06-207

Sigma-Aldrich

Anti-Lyn Antibody

serum, Upstate®

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

rabbit

品質等級

抗體表格

serum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

物種活性

human

製造商/商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... LYN(4067)

特異性

two known forms of human Lyn

免疫原

peptide (NKQQRPVPESQL-LPGQRFQT) corresponding to residues 39-58 of human Lyn

應用

Anti-Lyn Antibody detects level of Lyn & has been published & validated for use in IP & WB.

品質

routinely evaluated by immunoblot on RIPA lysates from human A431 cells

標靶描述

53 and 56kDa

外觀

whole antiserum containing 0.05% sodium azide

分析報告

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析證明 (COA)

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Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling
Wan, Y., et al
The Journal of Biological Chemistry, 272, 17209-17215 (1997)
B M Vonakis et al.
The Journal of biological chemistry, 272(38), 24072-24080 (1997-09-20)
Aggregation of the high affinity receptor for IgE (FcepsilonRI) leads to the phosphorylation of tyrosines on the beta and gamma chains of the receptor by the Src family kinase Lyn. We have studied the interaction between Lyn and the FcepsilonRI
Mirela Goldenberg-Furmanov et al.
Cancer research, 64(3), 1058-1066 (2004-02-12)
The Src-related protein kinase Lyn plays an important role in B-cell activation. However, several lines of evidence suggest that it is also involved in the control of cellular proliferation and the inhibition of apoptosis. We have discovered that Lyn is
J Holland et al.
The Journal of biological chemistry, 272(14), 9108-9112 (1997-04-04)
Intercellular adhesion molecule 1 (ICAM-1) (CD54) is an adhesion molecule of the immunoglobulin superfamily. The interaction between ICAM-1 on B lymphocytes and leukocyte function-associated antigen 1 on T cells plays a major role in several aspects of the immune response
M E Bates et al.
American journal of respiratory cell and molecular biology, 18(1), 75-83 (1998-02-03)
Eosinophils are potent effector cells contributing to allergic inflammation and asthma. The differentiation, recruitment, and effector functions of eosinophils are greatly affected by interleukin (IL)-5. In the eosinophil, signal transduction pathways including Jak-STAT and Ras-Raf-MAP kinase are stimulated by IL-5

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