06-1385

Anti-PDX1 (goat) Antibody

serum, from goat

• 同義詞: pancreatic and duodenal homeobox 1, pancreatic-duodenal homeobox factor 1, somatostatin transcription factor 1, insulin promoter factor 1, homeodomain transcription factor, Insulin promoter factor 1, Somatostatin-transactivating factor 1, Insulin upstrea
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: goat
• 品質等級: 100
• 抗體表格: serum
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: human, mouse
• 技術: immunohistochemistry: suitable; western blot: suitable
• NCBI登錄號: NP_032840
• UniProt登錄號: P52946
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Pdx1(18609)

描述

一般說明

Transcription factor PDX1, also known as pancreatic and duodenal homeobox 1, activates expression of the insulin and somatostatin genes. This protein is a key regulator of islet peptide hormone expression and also plays an essential role in pancreatic development. It has been shown to interact with the basic helix-loop-helix domains of TCF3(E47) and NEUROD1 and with HMG-I(Y). This protein also interacts with the methyltransferase SETD7. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

免疫原

Recombinant protein corresponding to the N-terminus of mouse PDX1.

應用

Anti-PDX1 (goat) Antibody is a Goat Polyclonal Antibody for detection of PDX1 also known as pancreatic & duodenal homeobox 1, somatostatin transcription factor 1, Insulin promoter factor 1 & has been validated in WB & IHC.

Immunohistochemistry Analysis: 1:400 dilution from a represenative lot detected PDX1 in normal human pancreas tissue.

品質

Evaluated by Western Blot in mouse pancreatic β T-cell lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected PDX1 on 10 µg of mouse pancreatic β T-cell lysate.

標靶描述

~ 39 kDa

外觀

Unpurified goat polyclonal serum containing 0.05% sodium azide.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1