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Merck
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重要文件

05-882

Sigma-Aldrich

Anti-Parkin Antibody, clone PRK8

ascites fluid, clone PRK8, Upstate®

同義詞:

Anti-AR-JP, Anti-LPRS2, Anti-PARK2, Anti-PDJ

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

ascites fluid

抗體產品種類

primary antibodies

無性繁殖

PRK8, monoclonal

物種活性

human, mouse

製造商/商標名

Upstate®

技術

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... PARK2(5071)

特異性

Parkin

免疫原

Full length recombinant human Parkin. Epitope has been mapped to the second ring domain (aa 399-465)

應用

Anti-Parkin Antibody, clone PRK8 detects level of Parkin & has been published & validated for use in IP, WB, IC, IH.

品質

routinely evaluated by immunoblot on RIPA lysates from HEK293 cells

標靶描述

52kDa May be observed as a doublet at 52 and 46kDa

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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Are ubiquitination pathways central to Parkinson's disease?
Giasson, Benoit I and Lee, Virginia M-Y
Cell, 114, 1-8 (2003)
Molecular pathways of neurodegeneration in Parkinson's disease.
Dawson, Ted M and Dawson, Valina L
Science (New York, N.Y.), 302, 819-822 (2003)
Genotype-phenotype correlation: familial Parkinson disease.
Mori, Hideo, et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 23, 90-94 (2003)
Nobutaka Hattori et al.
Lancet (London, England), 364(9435), 722-724 (2004-08-25)
The cause and pathogenesis of Parkinson's disease remain unknown; mitochondrial dysfunction, oxidative damage, environmental factors, and genetic predisposition might all be involved. Identification of the causative genes for familial Parkinson's diseases allow study of the pathogenesis of the disease at
Keiji Tanaka et al.
Biochimica et biophysica acta, 1695(1-3), 235-247 (2004-12-02)
The ubiquitin-proteasome system (UPS) is important for intracellular proteolysis, and is responsible for a diverse array of biologically important cellular processes, such as cell-cycle progression, signaling cascades and developmental programs. This system is also involved in the protein quality control

文章

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle them.

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