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Merck
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重要文件

05-780

Sigma-Aldrich

Anti-Akt3/PKBγ Antibody, clone GMA104

clone GMA104, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified antibody

抗體產品種類

primary antibodies

無性繁殖

GMA104, monoclonal

物種活性

human

製造商／商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG2a

NCBI登錄號

NM_005465

UniProt登錄號

Q9Y243

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... AKT3(10000)

特異性

Predicted to cross-react with mouse and rat based on sequence homology.
RhoA

免疫原

peptide corresponding to amino acids 119-131 (CSPTSQIDNIGEE) of human Akt3/PKBγ

應用

Research Category
Signaling
Research Sub Category
PI3K, Akt, & mTOR Signaling
This Anti-Akt3/PKBγ Antibody, clone GMA104 is validated for use in IP, WB for the detection of Akt3/PKBγ.

品質

routinely evaluated by immunoblot on RIPA lysates from Jurkat or HL-60 cells

標靶描述

~60kDa

外觀

Protein A purified
Buffered solution containing 0.1M Tris-Glycine, 0.15M NaCl, 0.05% Sodium Azide, pH 7.4.
Format: Purified

儲存和穩定性

Stable for 1 year at 2-8°C from date of receipt.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

分析證明 (COA)

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Aroa Soriano et al.
Oncotarget, 7(8), 9271-9287 (2016-01-30)
Despite multimodal therapies, a high percentage of high-risk neuroblastoma (NB) become refractory to current treatments, most of which interfere with cell cycle and DNA synthesis or function, activating the DNA damage response (DDR). In cancer, this process is frequently altered
Conrad P Hodgkinson et al.
Biochemistry, 41(32), 10351-10359 (2002-08-07)
Protein kinase B (PKB), also known as Akt, is a serine/threonine protein kinase controlled by insulin, various growth factors, and phosphatidylinositol 3-kinase. Full activation of the PKB enzyme requires phosphorylation of a threonine in the activation loop and a serine
The Akt isoforms are present at distinct subcellular locations.
Santi, SA; Lee, H
American Journal of Physiology. Cell Physiology null

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