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Merck
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重要文件

05-170

Sigma-Aldrich

Anti-IL-2 Rα Antibody, clone 7G7/B6

clone 7G7/B6, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

7G7/B6, monoclonal

物種活性

human

製造商/商標名

Upstate®

技術

dot blot: suitable
immunocytochemistry: suitable

同型

IgG2a

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

目標翻譯後修改

unmodified

基因資訊

human ... IL2RA(3559)

特異性

Recognizes interleukin-2 receptor.

免疫原

Whole cells expressing human IL-2 Receptor α

應用

Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
This Anti-IL-2 Rα Antibody, clone 7G7/B6 is validated for use in DB, IC for the detection of IL-2 Rα.

品質

routinely evaluated on ice cold ethanol/acetic acid [95:5] fixed phytohemagglutinin (PHA)-treated Jurkat T lymphocytes

標靶描述

55 kDa

外觀

Protein G Purified
Format: Purified
Protein G Purified immunoglobulin in Protein G Purified immunoglobulin in 0.1M Tris-glycine, pH 7.4, 0.15M NaCl with 0.05% sodium azide as a preservative.

儲存和穩定性

Lyophilized: 2 years at -20°C; Rehydrated: 6 months at -20°C

分析報告

Control
Lung tissue

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1


分析證明 (COA)

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A monoclonal antibody 7G7/B6, binds to an epitope on the human interleukin-2 (IL-2) receptor that is distinct from that recognized by IL-2 or anti-Tac.
Rubin, L A, et al.
Hybridoma, 4, 91-102 (1985)
P D Tahiliani et al.
The Journal of biological chemistry, 272(12), 7892-7898 (1997-03-21)
Integrin-mediated adhesion of cells to extracellular matrix proteins triggers a variety of intracellular signaling pathways including a cascade of tyrosine phosphorylations. In many cell types, the cytoplasmic focal adhesion tyrosine kinase, FAK, appears to be the initial protein that becomes
K S Lai et al.
The Journal of biological chemistry, 270(42), 25028-25036 (1995-10-20)
Signal transduction of cytokine receptors is mediated by the JAK family of tyrosine kinases. Recently, the kinase partners for the interleukin (IL)-2 receptor have been identified as JAK1 and JAK3. In this study, we report the identification of splice variants
Junya Tomida et al.
Nucleic acids research, 41(14), 6930-6941 (2013-06-01)
When DNA replication is stalled at sites of DNA damage, a cascade of responses is activated in the cell to halt cell cycle progression and promote DNA repair. A pathway initiated by the kinase Ataxia teleangiectasia and Rad3 related (ATR)
Kevin Lu et al.
Cancer research, 77(11), 2881-2892 (2017-04-19)
NRF2 is a transcription factor serving as a master regulator of the expression of many genes involved in cellular responses to oxidative and other stresses. In the absence of stress, NRF2 is constantly synthesized but maintained at low levels as

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