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Merck
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Key Documents

05-149

Sigma-Aldrich

Anti-FGFR1 Antibody, clone 19B2

clone 19B2, Upstate®, from mouse

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About This Item

分類程式碼代碼:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物源

mouse

品質等級

100

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

19B2, monoclonal

物種活性

human, rat

製造商／商標名

Upstate®

技術

immunoprecipitation (IP): suitable
western blot: suitable

同型

IgG1

NCBI登錄號

NM_015850.3
NM_023105.2
NM_023106.2
NM_023107.2
NM_023108.2
NM_023110.2
NM_023111.2

UniProt登錄號

P11362

運輸包裝

wet ice

目標翻譯後修改

unmodified

基因資訊

human ... FGFR1(2260)

特異性

extra cellular domain for both (alpha and beta) human FGF receptor

免疫原

E. coli fusion protein corresponding to amino acids 23-325 of human FGF receptor beta (Flg)

應用

Anti-FGFR1 Antibody, clone 19B2 detects level of FGFR1 & has been published & validated for use in IP & WB.
Research Category
Signaling
Research Sub Category
Growth Factors & Receptors

品質

routinely evaluated in sFGFR-1 (obtained from Alexis Biochemicals, Catalog # SFC-015)

標靶描述

110 kDa

外觀

Protein G Chromatography
0.1M Tris-glycine, pH 7.4, 0.15M NaCl containing 0.05% sodium azide
Format: Purified

儲存和穩定性

2 years at -20°C or 2 months at 4°C

法律資訊

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

Not applicable

閃點（°C）

Not applicable

分析證明 (COA)

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J Z Hou et al.
Science (New York, N.Y.), 251(4994), 665-668 (1991-02-08)
Changes in heparin-binding fibroblast growth factor gene expression and receptor phenotype occur during liver regeneration and in hepatoma cells. The nucleotide sequence of complementary DNA predicts that three amino-terminal domain motifs, two juxtamembrane motifs, and two intracellular carboxyl-terminal domain motifs
Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo.
M Wagner, M E Lopez, M Cahn, M Korc
Gastroenterology null
X Guillonneau et al.
Molecular biology of the cell, 9(10), 2785-2802 (1998-10-08)
Fibroblast growth factors (FGF) 1 and 2 and their tyrosine kinase receptor (FGFR) are present throughout the adult retina. FGFs are potential mitogens, but adult retinal cells are maintained in a nonproliferative state unless the retina is damaged. Our work
Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms.
Xu, J, et al.
The Journal of Biological Chemistry, 267, 17792-17803 (1992)
Y Mazaki et al.
Molecular biology of the cell, 12(3), 645-662 (2001-03-17)
Paxillin acts as an adaptor protein in integrin signaling. We have shown that paxillin exists in a relatively large cytoplasmic pool, including perinuclear areas, in addition to focal complexes formed at the cell periphery and focal adhesions formed underneath the
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