05-1362

Anti-RING1 Antibody, clone 4D6

clone 4D6, from mouse

• 同義詞: Polycomb complex protein RING1, ring finger protein 1
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: mouse
• 品質等級: 100
• 抗體表格: purified antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: 4D6, monoclonal
• 物種活性: mouse, human
• 技術: immunocytochemistry: suitable; western blot: suitable
• 同型: IgG2aκ
• NCBI登錄號: NP_002922.2
• UniProt登錄號: Q06587
• 運輸包裝: wet ice
• 目標翻譯後修改: unmodified
• 基因資訊: human ... RING1(6015)

描述

一般說明

RING1 belongs to the RING finger family, members of which are characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain.

特異性

This antibody detects RING1.

免疫原

GST-tagged recombinant protein corresponding to RING1.

應用

Immunocytochemistry: Representative lot data.
A 1:500 dilution of a previous lot was used in immunocytochemistry on NIH/3T3 and A431 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

Use Anti-RING1 Antibody, clone 4D6 (Mouse Monoclonal Antibody) validated in WB, ICC to detect RING1 also known as Polycomb complex protein RING1.

品質

Evaluated by western blot on HEK293 cell lysate.

Western Blot Analysis: 0.5-2 µg/mL of this antibody detected RING1 in HEK293 cell lysate.

標靶描述

~42 kDa

外觀

Protein G Purified

Format: Purified

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

儲存和穩定性

Stable for 1 year at 2-8ºC from date of receipt.

分析報告

Control
HEK293 cell lysate

其他說明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable