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Z-004

Supelco

扎来普隆标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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About This Item

經驗公式（希爾表示法）:
C17H15N5O
CAS號碼:
151319-34-5
分子量：:
305.33
EC號碼:
200-659-6
分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material

品質等級

300

形狀

liquid

特點

Snap-N-Spike®/Snap-N-Shoot®

包裝

ampule of 1 mL

製造商／商標名

Cerilliant®

濃度

1.0 mg/mL in methanol

技術

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

應用

clinical testing

格式

single component solution

儲存溫度

−20°C

SMILES 字串

CCN(C(C)=O)c1cccc(c1)-c2ccnc3c(cnn23)C#N

InChI

1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3

InChI 密鑰

HUNXMJYCHXQEGX-UHFFFAOYSA-N

基因資訊

human ... GABRA1(2554) , GABRB1(2560) , GABRG2(2566)

相關類別

一般說明

扎来普隆是一种非苯二氮卓类“Z药”，商品名为Sonata®或Starnoc，用于治疗失眠。扎来普隆经常因其改变精神的作用而被非法滥用。该经认证的加标溶液®适用于尿液药物检测、临床毒理学和法医分析的LC/MS或GC/MS应用。

應用


  • Controlled pore glass beads: Controlled pore glass can be employed for sustainable functionalized metal-organic frameworks for CO2 separation, showcasing the material′s effectiveness in environmental applications due to its high BET surface area which enhances gas adsorption properties (Babar et al., 2021).

  • Porous glass for protein adsorption: Mesoporous nano-bioglass for controlled drug release, highlights the application of controlled pore glass with high surface areas in pharmaceutical formulations to enhance the delivery and efficacy of therapeutic agents (Shoaib et al., 2017).

  • Surface characterization materials: It can be employed for the contact angle hysteresis of materials with controlled pore structures, to understand the wetting properties of high surface area materials like controlled pore glass, which is critical in various industrial and biomedical applications (Salmas and Androutsopoulos, 2001).


法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
Sonata is a registered trademark of King Pharmaceuticals Research and Development, Inc.

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 1

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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Adam R Lancaster et al.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 21(6), 658-665 (2012-02-10)
To summarize the signalment, clinical signs observed, time to onset of clinical signs, duration of clinical signs, and the outcome in a large case series of nonbenzodiazepine sleep aid ingestions in dogs, including 2 sleep aids that have not been
Karthik Y Janga et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 80(2), 347-357 (2011-11-02)
The present systematic study focused to investigate the combined advantage of proliposomes and surface charge for improved oral delivery of zaleplon. The zaleplon loaded proliposomes were prepared using hydrogenated soyphosphatidylcholine (HSPC) and cholesterol (CHOL) in varying ratios, and the optimized
David J Greenblatt et al.
Biopharmaceutics & drug disposition, 32(9), 489-497 (2011-09-22)
Two investigations aimed to define the pharmacokinetic profile of a modified-release preparation of zaleplon (SKP-1041). Protocol SOM001 was a 5-way crossover, double-blind, randomized trial comparing three novel modified-release formulations of zaleplon 15 mg (SKP-1041A, SKP-1041B, SKP-1041C) to placebo and immediate-release
Kirsten Wiese Simonsen et al.
Journal of analytical toxicology, 34(6), 332-341 (2010-07-29)
An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS-MS) method for detection of 23 benzodiazepines and related compounds in whole blood was developed and validated. The method is used for screening and quantitation of benzodiazepines in whole blood received from autopsy cases
Michael J Avram et al.
Journal of clinical pharmacology, 53(2), 140-150 (2013-02-26)
Pharmacokinetics, pharmacodynamics, safety, and tolerability of inhaled zaleplon were assessed in healthy volunteers. Forty participants received 0.5, 1, 2, or 4 mg zaleplon or placebo as a thermally generated aerosol in a randomized, double-blind, parallel-group, dose escalation study. Blood was
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文章

HPLC Analysis of Z-Drugs on Ascentis® Express ES-Cyano 2.0 μm

Separation of Zolpidem phenyl-4-carboxylic acid solution, 500 μg/mL in acetonitrile: water (1:1), ampule of 1 mL, certified reference material; Zopiclone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material; Zopiclone-N-oxide solution, 100 μg/mL (Methanol with 1% 1 M HCl), ampule of 1 mL, certified reference material; Zolpidem tartrate solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material; Zaleplon solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material; N-Desmethylzopiclone

HPLC Analysis of Z-Drugs on Ascentis® Express ES-Cyano 2.0 μm

An rapid method for the siµLtaneous determination of the Z-drugs or sleep aids: zopiclone, zolpidem, and zaleplon is presented here. The need for greater analytical capacity and throughput for the analysis of sleep aid medicines (Z-drugs) in forensic toxicology laboratories can be met by the use of fast Ascentis Express 2.0 micron Fused Core UHPLC Columns.

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