V-063

泛酸-¹³C₃,¹⁵N半钙盐标准液 半钙盐 溶液

100 μg/mL (90:10 Methanol:Water, (as free acid)), certified reference material, ampule of 1 mL, Cerilliant^®

• 經驗公式（希爾表示法）: ¹³C₃C₆H₁₆¹⁵NO₅ · 0.5Ca
• CAS號碼: 356786-94-2
• 分子量：: 242.24
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL (90:10 Methanol:Water, (as free acid))
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C

描述

一般說明

An internal standard suitable for quantitation of pantothenic acid levels and testing applications including clinical and diagnostic testing or quality control testing of vitamin supplements, fortified foods or pharmaceutical preparations. Pantothenic acid, also known as Vitamin B5, is an essential water-soluble B vitamin that is involved in the coenzyme A (CoA) synthesis.

應用

• Enzyme inhibition studies: Stable isotope-labeled pantothenic acid is used in X-ray crystallography and NMR studies to understand the mechanism of homotropic inhibition in enzyme reactions, specifically pantothenate synthetase. Such studies are essential for drug design targeting metabolic pathways, enhancing the effectiveness of treatments involving vitamin B5 pathways (Chakrabarti et al., 2010).


• NMR structural analysis: The labeled compound aids in the NMR structural elucidation of enzymes such as ketopantoate reductase, helping to determine its role in biological systems. This analysis is crucial for developing drugs that can manipulate these enzymatic pathways, impacting treatments for conditions requiring metabolic modulation (Headey et al., 2008).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P302 + P352 + P312 - P304 + P340 + P311 - P370 + P378 - P403 + P235
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup