V-027

(±)-O-去甲基文拉法辛-D₆ 溶液

100 μg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 同義詞: (±)−O-去甲基文拉法辛-D₆ 溶液
• 經驗公式（希爾表示法）: C₁₆H₁₉D₆NO₂
• CAS號碼: 1062605-69-9
• 分子量：: 269.41
• EC號碼: 200-659-6
• MDL號碼: MFCD07369295
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329828969
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: (Snap-N-Spike^®)
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: clinical testing
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: OC1=CC=C(C(CN(C([2H])([2H])[2H])C([2H])([2H])[2H])C2(O)CCCCC2)C=C1
• InChI: 1S/C16H25NO2/c1-17(2)12-15(13-6-8-14(18)9-7-13)16(19)10-4-3-5-11-16/h6-9,15,18-19H,3-5,10-12H2,1-2H3/i1D3,2D3
• InChI 密鑰: KYYIDSXMWOZKMP-WFGJKAKNSA-N

描述

一般說明

经认证的参比溶液，适合用作内标，通过LC/MS或GC/MS定量尿液中O-去甲基文拉法辛水平或同位素稀释方法，以进行临床毒理学，尿液药物测试或法医分析。O-去甲基文拉法辛也称为去甲文拉法辛，是一种SNRI抗抑郁药，以商品名Pristiq^®销售，用于治疗抑郁症。O-去甲基文拉法辛也是文拉法辛的主要尿代谢产物，文拉法辛是一种SNRI抗抑郁药，以Effexor^®或Efexor出售，用于治疗重度抑郁症、广泛性焦虑症和其他与抑郁症相关的焦虑症。

應用

• Hydrodesulfurization research using pharmacosiderite Mo(4)P(3)O(16): This study utilized the microporous catalytic activity of synthesized Mo(4)P(3)O(16) under moderate temperatures for hydrodesulfurization, showing its potential in refining processes relevant to forensic toxicology for substance identification, including antidepressant drug metabolites (Ishikawa et al., 2024).
• Synthesis of acyl cyclopentaquinolinones: Research demonstrated the construction of acyl cyclopentaquinolinones with potential implications for the synthesis and analysis of stable isotope-labeled compounds, helping to understand the biochemistry and metabolism of antidepressants (Xue et al., 2024).
• Nutraceutical applications from biomass: The production and characterization of xylooligosaccharides from lignocellulosic biomass were reviewed, relevant for pharmacokinetic research by providing insights into plant-derived compound processing and applications, influencing stable isotope-labeled compound studies (Kumar et al., 2024).
• Adverse event detection in pharmaceutical care: This study evaluated deep learning models for detecting adverse events from pharmaceutical care records, offering a methodological approach that could be adapted for monitoring effects related to antidepressant drugs in clinical settings (Nishioka et al., 2024).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Effexor is a registered trademark of American Home Product Corp.

Pristiq is a registered trademark of Wyeth LLC

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F
• 閃點（°C）: 9.7 °C