S-085

AB-PINACA 5-Pentanoic acid metabolite

100 μg/mL in methanol, certified reference material, Cerilliant^®

• 經驗公式（希爾表示法）: C₁₈H₂₄N₄O₄
• CAS號碼: 1630022-93-3
• 分子量：: 360.41
• 分類程式碼代碼: 41116107
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: Snap-N-Spike^®/Snap-N-Shoot^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 100 μg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology; forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C

描述

一般說明

AB-PINACA 5-Pentanoic acid metabolite is a major urinary metabolite of the synthetic cannabinoid AB-PINACA. Over the past couple of years, clusters of cases of severe toxic effects and deaths related to AB-PINACA use have increased in the United States. This certified reference solution is suitable for use in synthetic cannabinoid testing methods by LC/MS or GC/MS for applications in clinical toxicology, urine drug testing, and forensic analysis.

應用

• HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study employed the LiChrospher^® 100 RP-18 endcapped (5µm) LICHROCART^™ 125-4.6 column for high-performance liquid chromatography analysis of chlorambucil and valproic acid in plasma. The method facilitated efficient separation and detection, critical for evaluating combined chemotherapy protocols (Lipska K et al., 2021).


• Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: This research utilized the LiChrospher^® 100 RP-18 endcapped (5µm) LICHROCART^™ 125-4.6 column to develop and validate a robust HPLC method for the quantification of ropinirole hydrochloride. The study demonstrated the column′s capability in achieving high sensitivity and precision in pharmaceutical analysis (Fatima S et al., 2019).


• Determination of retinol and retinyl esters in human plasma by high-performance liquid chromatography with automated column switching and ultraviolet detection.: The LiChrospher^® 100 RP-18 endcapped (5µm) LICHROCART^™ 125-4.6 column was applied in the analysis of retinol and its esters in human plasma. This study showcased the column′s efficiency in separating closely related compounds, essential for accurate biochemical assays (Hartmann S et al., 2001).


• Rapid, highly sensitive method for the determination of morphine and its metabolites in body fluids by liquid chromatography-mass spectrometry.: This investigation leveraged the LiChrospher^® 100 RP-18 endcapped (5µm) LICHROCART^™ 125-4.6 column to develop a sensitive LC-MS method for morphine and its metabolites. The column′s performance ensured reliable detection in forensic and clinical toxicology (Schänzle G et al., 1999).


• Determination of 13-cis-3-hydroxyretinoic acid, all-trans-3-hydroxyretinoic acid and their 4-oxo metabolites in human and animal plasma by high-performance liquid chromatography with automated column switching and UV detection.: This study used the LiChrospher^® 100 RP-18 endcapped (5µm) LICHROCART^™ 125-4.6 column for the simultaneous analysis of retinoic acid metabolites, highlighting its application in pharmacokinetics and metabolism research (Wyss R et al., 1998).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

LICHROCART is a trademark of Merck KGaA, Darmstadt, Germany

LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: 49.5 °F - closed cup
• 閃點（°C）: 9.7 °C - closed cup