C-035

(±)-可替宁-D_{3标准液 CRM} 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• 同義詞: (+/-)-可替宁-D_{3标准液 CRM} 溶液
• 經驗公式（希爾表示法）: C₁₀H₉D₃N₂O
• CAS號碼: 110952-70-0
• 分子量：: 179.23
• EC號碼: 200-659-6
• MDL號碼: MFCD00083283
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329774776
• NACRES: NA.24

屬性

• 等級: certified reference material
• 形狀: liquid
• 特點: SNAP-N-SPIKE^®, SNAP-N-SHOOT^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• 濃度: 1.0 mg/mL in methanol
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• InChI: 1S/C10H12N2O/c1-12-9(4-5-10(12)13)8-3-2-6-11-7-8/h2-3,6-7,9H,4-5H2,1H3/i1D3
• InChI 密鑰: UIKROCXWUNQSPJ-FIBGUPNXSA-N

描述

一般說明

可替宁是存在于烟草中的一种生物碱，也是尼古丁的主要尿液代谢物。这种稳定标记的内标适用于尼古丁测试或尼古丁生物标记物的临床和诊断测试，通过GC/MS或LC-MS/MS法定量尿液、血液和唾液中的可替宁水平。

應用

• (±)-Cotinine-d₃ solution in nicotine metabolism research: This stable isotope-labeled compound is utilized in the HPLC-MS analysis of nicotine and cotinine across various biological matrices, highlighting its critical role in advancing our understanding of nicotine metabolism and exposure in biomedical studies (Jin et al., 2022).


• Biomarker analysis in passive smoking: Cotinine-d₃ serves as an internal standard in the precise quantification of urinary cotinine, aiding in the assessment of second-hand smoke exposure, particularly in pediatric health studies (Wang et al., 2014).


• Enhanced analytical techniques for smoking cessation: Employed in a sophisticated UPLC-MS/MS setup, cotinine-d₃ is crucial for quantifying smoking-related biomarkers in clinical trials aimed at evaluating smoking cessation interventions, ensuring accurate and sensitive biomarker tracking (Dobrinas et al., 2011).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS06,GHS08
• 訊號詞: Danger
• 危險聲明: H225,H301 + H311 + H331,H370
• 防範說明: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• 危險分類: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• 標靶器官: Eyes
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 51.8 °F - closed cup
• 閃點（°C）: 11.0 °C - closed cup