A-003

6-乙酰吗啡, 100 μg/mL 溶液

100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant^®

• 同義詞: 6-乙酰吗啡 溶液
• 經驗公式（希爾表示法）: C₁₉H₂₁NO₄
• CAS號碼: 2784-73-8
• 分子量：: 327.37
• EC號碼: 200-835-2
• MDL號碼: MFCD00467140
• 分類程式碼代碼: 41116107
• PubChem物質ID: 329770565
• NACRES: NA.24

屬性

• 等級: certified reference material
• 品質等級: 300
• 形狀: liquid
• 特點: SNAP-N-SPIKE^®. SNAP-N-SHOOT^®
• 包裝: ampule of 1 mL
• 製造商／商標名: Cerilliant^®
• drug control: Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)
• 濃度: 100 μg/mL in acetonitrile
• 技術: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• 應用: forensics and toxicology
• 格式: single component solution
• 儲存溫度: −20°C
• SMILES 字串: CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35
• InChI: 1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1
• InChI 密鑰: JJGYGPZNTOPXGV-SSTWWWIQSA-N

描述

一般說明

6-乙酰吗啡又称 6-单乙酰吗啡或 6-MAM，是海洛因的活性代谢产物，并且是使用海洛因的生物标志物。此认证加标溶液^®适合用作法医分析、临床毒理学、尿液药物测试或止痛处方监测中 GC/MS 或 LC/MS 方法的校准和对照的起始材料。

應用

• Drug use monitoring: The utility of 6-acetylmorphine as a specific biomarker in workplace drug testing for identifying illicit heroin use among morphine-positive urine specimens was highlighted, affirming its importance in forensic and clinical toxicology (Vikingsson et al., 2024).


• Physiological monitoring technology: The detection of 6-acetylmorphine in sweat at the molecular level demonstrates the potential of the wearable SERS sensor in monitoring drug use (Liu et al., 2024).


• Drug effect attenuation research: A bivalent conjugate vaccine inducing dual immunogenic responses was studied to attenuate the effects of heroin and fentanyl in mice, utilizing 6-acetylmorphine as a component, demonstrating its potential in therapeutic developments (Barrientos et al., 2021).


• Behavioral toxicology: The determination of drugs of abuse in hair samples using LC-MS/MS, which included 6-acetylmorphine, provided vital data for investigations related to suicide attempts, highlighting its utility in clinical and forensic toxicology (Cardoso et al., 2022).

法律資訊

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

安全資訊

• 象形圖: GHS02,GHS07
• 訊號詞: Danger
• 危險聲明: H225,H302 + H312 + H332,H319
• 防範說明: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• 儲存類別代碼: 3 - Flammable liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: 35.6 °F - closed cup
• 閃點（°C）: 2 °C - closed cup