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LM1304

Avanti

17:0-14:1 PS

Avanti Research™ - A Croda Brand LM1304, methanol solution

同義詞:

1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine (ammonium salt)

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About This Item

經驗公式（希爾表示法）:
C37H73N2O10P
CAS號碼:
1036814-91-1
分子量：:
736.96
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

methanol solution

包裝

pkg of 1 × 1 mL (LM1304-1EA)

製造商／商標名

Avanti Research™ - A Croda Brand LM1304

濃度

~10 μg/mL (Refer to C of A for lot specific concentration. )

應用

lipidomics
metabolomics

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCC/C=C\CCCC)=O)COC(CCCCCCCCCCCCCCCC)=O.[NH4+]

InChI 密鑰

ZBOCVGFQVSWMHT-BPNWTSRKSA-N

相關類別

一般說明

Phosphatidylserine (PS) is an acidic phospholipid present in human cerebral cortex. It is abundant in the inner leaflet of the plasma membrane in neural tissues.

應用

17:0-14:1 PS or 1-heptadecanoyl-2-(9Z-tetradecenoyl)-sn-glycero-3-phospho-L-serine has been used as an internal standard:
  • for the detection of lipids by tandem mass spectrometry (MS/MS)
  • to determine lipid concentration in human primary myotubes lipid extracts by mass spectrometry (MS) analysis
  • for phospholipid quantification by MS
  • for lipid extraction by methyl tert-butyl ether (MTBE) method
  • for lipid quantification using liquid chromatography (LC)-MS

生化／生理作用

Phosphatidylserine (PS) is associated with the Akt, protein kinase C (PKC) and Raf-1 signaling. It supports neuronal survival, neurite growth and synaptogenesis.

包裝

2 mL Amber Glass Sealed Ampule (LM1304-1EA)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

標靶器官

Eyes

儲存類別代碼

3 - Flammable liquids

水污染物質分類（WGK）

WGK 2

閃點（°F）

49.5 °F - closed cup

閃點（°C）

9.7 °C - closed cup

從最近期的版本中選擇一個：

分析證明 (COA)

Lot/Batch Number

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Hee-Yong Kim et al.
Progress in lipid research, 56, 1-18 (2014-07-06)
Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the inner leaflet of the plasma membrane in neural tissues. PS is synthesized from phosphatidylcholine or phosphatidylethanolamine by exchanging the base head group with serine, and this reaction is
Ursula Loizides-Mangold et al.
Journal of lipid research, 53(8), 1522-1534 (2012-05-26)
Glycosylphosphatidylinositol (GPI) anchor biosynthesis takes place in the endoplasmic reticulum (ER). After protein attachment, the GPI anchor is transported to the Golgi where it undergoes fatty acid remodeling. The ER exit of GPI-anchored proteins is controlled by glycan remodeling and
Ulrike Bruning et al.
Cell metabolism, 28(6), 866-880 (2018-08-28)
The role of fatty acid synthesis in endothelial cells (ECs) remains incompletely characterized. We report that fatty acid synthase knockdown (FASNKD) in ECs impedes vessel sprouting by reducing proliferation. Endothelial loss of FASN impaired angiogenesis in vivo, while FASN blockade reduced

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