跳轉至內容
Merck
全部照片(1)

Key Documents

890898P

Avanti

DOTMA

Avanti Research - A Croda Brand

同義詞:

1,2-二-O-十八烯酰-3-三甲铵丙烷(氯化盐)

登入查看組織和合約定價


About This Item

經驗公式(希爾表示法):
C42H84ClNO2
CAS號碼:
分子量::
670.57
分類程式碼代碼:
12352211
NACRES:
NA.25

形狀

powder

包裝

pkg of 2 × 100 mg (890898P-200mg)
pkg of 1 × 25 mg (890898P-25mg)

製造商/商標名

Avanti Research - A Croda Brand

應用

advanced drug delivery

脂質類型

cationic lipids
transfection

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(C)C)(OCCCCCCCC/C=C\CCCCCCCC)COCCCCCCCC/C=C\CCCCCCCC.[Cl-]

尋找類似的產品? 前往 產品比較指南

應用

DOTMA适合作为miRNA递送系统的结构单元并用于制备。

生化/生理作用

DOTMA是一种阳离子脂质,可用作基因治疗的非病毒载体。它对体外和体内基因转染均有作用。DOTMA可使脂质体带上正电荷,因此促成更高效的脂质体-细胞膜相互作用。

包裝

5 mL透明玻璃密封安瓿瓶(890898P-200mg)
5 mL透明玻璃密封安瓿瓶(890898P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號,寫有 ‘Lot’或‘Batch’.。

已經擁有該產品?

您可以在文件庫中找到最近購買的產品相關文件。

存取文件庫

The use of cationic microbubbles to improve ultrasound-targeted gene delivery to the ischemic myocardium
Sun L, et al.
Biomaterials, 34(8), 2107-2116 (2013)
Yun Wu et al.
Molecular therapy. Nucleic acids, 2, e84-e84 (2013-04-18)
MicroRNA-29b (miR-29b) expression has been shown to be reduced in non-small-cell lung cancer (NSCLC) tissues. Here, we have identified the oncogene cyclin-dependent protein kinase 6 (CDK6) as a direct target of miR-29b in lung cancer. We hypothesized that in vivo
Jinhong Meng et al.
Scientific reports, 10(1), 1046-1046 (2020-01-25)
P53 mutations are responsible for drug-resistance of tumour cells which impacts on the efficacy of treatment. Alternative tumour suppressor pathways need to be explored to treat p53- deficient tumours. The E3 ubiquitin ligase, ITCH, negatively regulates the tumour suppressor protein
Jayesh A Kulkarni et al.
ACS nano, 12(5), 4787-4795 (2018-04-04)
Lipid nanoparticles (LNPs) containing short interfering RNA (LNP-siRNA) and optimized ionizable cationic lipids are now clinically validated systems for silencing disease-causing genes in hepatocytes following intravenous administration. However, the mechanism of formation and certain structural features of LNP-siRNA remain obscure.

我們的科學家團隊在所有研究領域都有豐富的經驗,包括生命科學、材料科學、化學合成、色譜、分析等.

聯絡技術服務