推薦產品
化驗
99% (TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (857410P-5mg)
pkg of 1 × 5 mg (857410P-5mg)
製造商/商標名
Avanti Research™ - A Croda Brand
脂質類型
bioactive lipids
運輸包裝
dry ice
儲存溫度
−20°C
SMILES 字串
C[C@@H](O)[C@H](NC(C(N1)=CC2=C1C=CC(OC)=C2)=O)C(NCCCCCCCCCCCCC)=O
InChI 密鑰
RAXJRRQLMVPSON-NLFFAJNJSA-N
一般說明
IG7 is a ceramide analog.
生化/生理作用
IG7 is potent in enhancing Fas ligand (FasL) induced apoptosis in colon carcinoma cells SW480 and RKO. IG7 enhances FasL mediated phosphorylation of p38 and janus kinase (JNK). IG7 enhances nuclear factor-kappa B (NF-κB) activation by FasL. IG7 exhibits low toxicity.
包裝
5ML Glass Amber Screw Cap Vial (857410P-1MG)
5ML Glass Amber Screw Cap Vial (857410P-5MG)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
Coe GL, et al.
Scientific Reports, 6, 30816-30816 (2016)
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