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重要文件

857410P

Avanti

IG7

Avanti Research - A Croda Brand, powder

同義詞:

N-((2S,3R)-3-hydroxy-1-oxo-1-(tridecylamino)butan-2-yl)-5-methoxy-1H-indole-2-carboxamide

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About This Item

經驗公式(希爾表示法):
C27H43N3O4
CAS號碼:
分子量::
473.65
分類程式碼代碼:
12352211
NACRES:
NA.25

化驗

99% (TLC)

形狀

powder

包裝

pkg of 1 × 1 mg (857410P-5mg)
pkg of 1 × 5 mg (857410P-5mg)

製造商/商標名

Avanti Research - A Croda Brand

脂質類型

bioactive lipids

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

C[C@@H](O)[C@H](NC(C(N1)=CC2=C1C=CC(OC)=C2)=O)C(NCCCCCCCCCCCCC)=O

InChI 密鑰

RAXJRRQLMVPSON-NLFFAJNJSA-N

一般說明

IG7 is a ceramide analog.

生化/生理作用

IG7 is potent in enhancing Fas ligand (FasL) induced apoptosis in colon carcinoma cells SW480 and RKO. IG7 enhances FasL mediated phosphorylation of p38 and janus kinase (JNK). IG7 enhances nuclear factor-kappa B (NF-κB) activation by FasL. IG7 exhibits low toxicity.

包裝

5ML Glass Amber Screw Cap Vial (857410P-1MG)
5ML Glass Amber Screw Cap Vial (857410P-5MG)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析證明 (COA)

Lot/Batch Number

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Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytes
Coe GL, et al.
Scientific Reports, 6, 30816-30816 (2016)

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