857324P

17:0 Cyclic LPA

Avanti Research^™ - A Croda Brand 857324P, powder

• 同義詞: 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt)
• 經驗公式（希爾表示法）: C₂₀H₄₂NO₆P
• CAS號碼: 2260669-82-5
• 分子量：: 423.52
• 分類程式碼代碼: 51191904
• NACRES: NA.25

屬性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 1 mg (857324P-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 857324P
• 脂質類型: phospholipids; cardiolipins
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: O=P1([O-])O[C@H](COC(CCCCCCCCCCCCCCCC)=O)CO1.[NH4+]
• InChI: 1S/C20H39O6P.H3N/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20(21)24-17-19-18-25-27(22,23)26-19;/h19H,2-18H2,1H3,(H,22,23);1H3/t19-;/m1./s1
• InChI 密鑰: QQOXNBRKDUFLHW-FSRHSHDFSA-N

描述

一般說明

Cyclic phosphatidic acid (cPA) is a naturally occurring analog of the growth factor-like phospholipid mediator, lysophosphatidic acid (LPA). The sn-2 hydroxy group of CPA forms a 5-membered ring with the sn-3 phosphate.

應用

17:0 Cyclic LPA or 1-heptadecanoyl-glycero-2,3-cyclic-phosphate (ammonium salt) has been used as an internal standard for the quantification of cyclic lysophosphatidic acid (LPA) esters in proton samples using reversed-phase ultra-performance liquid chromatography-tandem mass spectrometer (UPLC-MS/MS).

生化／生理作用

cPA affects numerous cellular functions, including anti-mitogenic regulation of the cell cycle, induction of stress fiber formation, inhibition of tumor cell invasion and metastasis, and regulation of differentiation and survival of neuronal cells.
Interestingly, many of these cellular responses caused by cPA oppose those of LPA despite the activation of apparently overlapping receptor populations.

包裝

5 mL Amber Glass Screw Cap Vial (857324P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 閃點（°F）: No data available
• 閃點（°C）: No data available