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850537P

Avanti

Facade^™-TEM

Name: Facade<SUP>™</SUP>-TEM
Brand: AVANTI

3α,7α,12α-tri-((O-β-D-maltopyranosyl)ethyloxy)-cholane, powder

同義詞:

FA-4

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About This Item

經驗公式（希爾表示法）:

C₆₆H₁₁₄O₃₆

CAS號碼:

1429405-96-8

分子量：:

1483.59

分類程式碼代碼:

12161902

NACRES:

NA.25

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Millipore

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化驗

>99% (TLC)

形狀

powder

分子量

1483.59 g/mol

包裝

pkg of 1 × 25 mg (850537P-25mg)

製造商／商標名

Avanti Research^™ - A Croda Brand 850537P

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@]12[C@]([C@](CC[C@@H](OCCO[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)[C@@H](CO)O3)C5)(C)[C@]5([H])C[C@H]2OCCO[C@@H]6[C@@H](O)[C@H](O)[C@@H](O[C@H]7[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O7)[C@H](CO)O6)([H])C[C@H](OCCO[C@

一般說明

Facade^™TEM/FA-4 (3α,7α,12α-tri-((O-β-D-maltopyranosyl)ethyloxy)-cholane) is a sterol-based/sugar-based facial amphiphile. It carries three sugar attachments on the steroid backbone.

生化／生理作用

Facade^™TEM/FA-4 (3α,7α,12α-tri-((O-β-D-maltopyranosyl)ethyloxy)-cholane) can be used in the preparation of micelles. It may also be used in the stabilization and crystallization of membrane proteins. FA-4 is not effective as a cystic fibrosis transmembrane conductance regulator (CFTR) solubilizer.

包裝

5 mL Amber Glass Screw Cap Vial (850537P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Facade is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids

分析證明 (COA)

輸入產品批次/批號來搜索分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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存取文件庫

Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins.

Sung Chang Lee et al.

Proceedings of the National Academy of Sciences of the United States of America, 110(13), E1203-E1211 (2013-03-13)

Amphiphile selection is a critical step for structural studies of membrane proteins (MPs). We have developed a family of steroid-based facial amphiphiles (FAs) that are structurally distinct from conventional detergents and previously developed FAs. The unique FAs stabilize MPs and

Designing facial amphiphiles for the stabilization of integral membrane proteins.

Qinghai Zhang et al.

Angewandte Chemie (International ed. in English), 46(37), 7023-7025 (2007-08-11)

A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR).

Ellen Hildebrandt et al.

Biochimica et biophysica acta, 1838(11), 2825-2837 (2014-07-30)

Structural knowledge of the cystic fibrosis transmembrane conductance regulator (CFTR) requires developing methods to purify and stabilize this aggregation-prone membrane protein above 1mg/ml. Starting with green fluorescent protein- and epitope-tagged human CFTR produced in mammalian cells known to properly fold

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

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Facade^™-TEM