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Key Documents

850395C

Avanti

18:3 (Cis) PC

Avanti Research - A Croda Brand 850395C

同義詞:

1,2-dilinolenoyl-sn-glycero-3-phosphocholine

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About This Item

經驗公式(希爾表示法):
C44H76NO8P
CAS號碼:
分子量::
778.05
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850395C-25mg)
pkg of 2 × 4 mL (850395C-200mg)

製造商/商標名

Avanti Research - A Croda Brand 850395C

濃度

10 mg/mL (850395C-25mg)
25 mg/mL (850395C-200mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine is an unsaturated glycerophospholipid, with substitution of two chains of linolenic acid at sn-1 and sn-2 positions of the glycerol backbone, along with choline as a headgroup.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

應用

18:3 (cis) PC or 1,2-dilinolenoyl-sn-glycero-3-phosphocholine:
  • might be used in aqueous lipid-trehalose formulations to assess the long-term storage stability of lyophilized liposomes
  • might be used in phospholipid monolayer to study the instability of unsaturated phospholipids at specified conditions
  • has been used in aqueous sugar formulations or liposome formulations to characterize its degradation during lyophilization

包裝

5 mL Clear Glass Sealed Ampule (850395C-200mg)
5 mL Clear Glass Sealed Ampule (850395C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

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象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

標靶器官

Central nervous system, Liver,Kidney

水污染物質分類(WGK)

WGK 3


分析證明 (COA)

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European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 85(2), 306-313 (2013-04-10)
As liquid liposomal formulations are prone to chemical degradation and aggregation, these formulations often require freeze drying (e.g., lyophilization) to achieve sufficient shelf-life. However, liposomal formulations may undergo oxidation during lyophilization and/or during prolonged storage. The goal of the current

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