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850346C

Avanti

14:1 (Δ9-Cis) PC

1,2-dimyristoleoyl-sn-glycero-3-phosphocholine, chloroform

同義詞:

1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-phosphocholine; PC(14:1(9Z)/14:1(9Z))

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About This Item

經驗公式(希爾表示法):
C36H68NO8P
CAS號碼:
分子量::
673.90
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

liquid

包裝

pkg of 1 × 2.5 mL (850346C-25mg)
pkg of 2 × 4 mL (850346C-200mg)

製造商/商標名

Avanti Research - A Croda Brand 850346C

濃度

10 mg/mL (850346C-25mg)
25 mg/mL (850346C-200mg)

脂質類型

cardiolipins
phospholipids

運輸包裝

dry ice

儲存溫度

−20°C

一般說明

Phosphatidylcholine (PC) belongs to the class of glycerophospholipid. It is the prime cellular phospholipid.
Phosphatidylcholine (PC) is a strong bilayer-forming lipid. It the most common phospholipid in mammalian membranes. It is also an important component of the mucosal layer of the colon.
The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

應用

14:1 (Δ9-Cis) PC has been used in the liposome preparation. It has also been used as an internal standard for the extraction of lipids from the interstitial fractions of lung tissues for electrospray ionisation-mass spectrometry (ESI-MS) analysis.

生化/生理作用

Phosphatidylcholine (PC) contributes to the membrane structure. Each cell type and tissue maintain a unique PC profile. PC plays a key role in cell signaling. Disruption in the homeostasis of PC leads to cell death in mammalian cells. PC is present in bile and aids in lipid emulsification in the diet. It is known to reduce cholesterol and triglyceride levels. It is administered for treating fat embolism and cardiac ischemia. Monounsaturated PC 14:1 (Δ9-Cis) is known to inhibit cell proliferation in different cell lines.
Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance. It is used to treat fat embolism. Phosphatidylcholine lowers the levels of cholesterol and triglycerides.

包裝

5 mL Clear Glass Sealed Ampule (850346C-200mg)
5 mL Clear Glass Sealed Ampule (850346C-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3

標靶器官

Liver,Kidney, Respiratory system

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

does not flash

閃點(°C)

does not flash


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存取文件庫

Phosphatidylcholine and cell death
Cui Z and Houweling M
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1585(2-3), 87-96 (2002)
Integrative Medicine - E-Book (2017)
Bilayer thickness and curvature influence binding and insertion of a pHLIP peptide
Karabadzhak AG, et al.
Biophysical Journal, 114(9), 2107-2115 (2018)
The Membranes of Cells (2016)
Interference of phosphatidylcholines with in vitro cell proliferation?no flock without black sheep
Werlein A, et al.
Biochimica et Biophysica Acta - Biomembranes, 1848(7), 1599-1608 (2015)

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