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Key Documents

850312P

Avanti

DOCPe

Avanti Research - A Croda Brand 850312P, powder

同義詞:

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethyl phosphate

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About This Item

經驗公式(希爾表示法):
C45H86NO8P
CAS號碼:
分子量::
800.14
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 200 mg (850312P-200mg)
pkg of 1 × 25 mg (850312P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 850312P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H]C(C[N+](C)(CCOP([O-])(OCC)=O)C)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O

一般說明

2-((2,3-bis(oleoyloxy)propyl)dimethylammonio)ethyl ethylphosphate (DOCPe) is a neutrally charged lipid.
Inverse-phosphocholine lipids, a remix of a common phospholipid, contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Therefore iPC lipids afford a unique opportunity to investigate the biophysical and bioactivity-related ramifications of a charge inversion at the bilayer surface.

應用

DOCPe is suitable for liposomes preparation.

包裝

20 mL Clear Glass Screw Cap Vial (850312P-200mg)
5 mL Clear Glass Sealed Ampule (850312P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


分析證明 (COA)

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存取文件庫

Charge and Coordination Directed Liposome Fusion onto SiO2 and TiO2 Nanoparticles
Wang X, et al.
Langmuir, 35(5), 1672-1681 (2018)
Emily K Perttu et al.
Journal of the American Chemical Society, 134(10), 4485-4488 (2012-03-01)
Zwitterionic inverse-phosphocholine (iPC) lipids contain headgroups with an inverted charge orientation relative to phosphocholine (PC) lipids. The iPC lipid headgroup has a quaternary amine adjacent to the bilayer interface and a phosphate that extends into the aqueous phase. Neutral iPC
Yibo Liu et al.
Langmuir : the ACS journal of surfaces and colloids, 34(32), 9337-9348 (2018-03-13)
Phospholipids are a major component of the cell membrane. In most natural phospholipids, the phosphate acts as a bridge, connecting the other portion of the polar headgroup with the hydrophobic tails. Such bridging phosphate is chemically quite inert. Synthetic lipids
Feng Wang et al.
Journal of the American Chemical Society, 137(36), 11736-11742 (2015-08-25)
Zwitterionic phosphocholine (PC) lipids are highly biocompatible, representing a major component of the cell membrane. A simple mixing of PC liposomes and silica (SiO2) surface results in liposome fusion with the surface and formation of supported lipid bilayers. However, the

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