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重要文件

840030P

Avanti

06:0 PS

1,2-dihexanoyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

同義詞:

PS(6:0/6:0)

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About This Item

經驗公式(希爾表示法):
C18H33NO10PNa
CAS號碼:
分子量::
477.42
分類程式碼代碼:
51191904
NACRES:
NA.25

化驗

>99% (TLC)

形狀

powder

包裝

pkg of 1 × 10 mg (840030P-10mg)
pkg of 1 × 25 mg (840030P-25mg)

製造商/商標名

Avanti Research - A Croda Brand 840030P

脂質類型

phospholipids
cardiolipins

運輸包裝

dry ice

儲存溫度

−20°C

SMILES 字串

[H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCC)=O)COC(CCCCC)=O.[Na+]

InChI

1S/C18H34NO10P.Na/c1-3-5-7-9-16(20)26-11-14(29-17(21)10-8-6-4-2)12-27-30(24,25)28-13-15(19)18(22)23;/h14-15H,3-13,19H2,1-2H3,(H,22,23)(H,24,25);/q;+1/p-1/t14-,15+;/m1./s1

InChI 密鑰

OPDYVXCKOQKYDZ-LIOBNPLQSA-M

一般說明

Phosphatidylserine (PS) is an acidic phospholipid. Approximately 15–33 mol% of PS is present in the inner leaflet of the plasma membrane.

應用

06:0 PS may be used to study its effect on α-syn (α-synuclein) oligomerization by DA (dopamine) and as a phospholipid substrate to determine the kinetic parameters for phospholipase C by chromogenic assay. It has also been used in the preparation of phospholipid vesicles.

生化/生理作用

Phosphatidylserine (PS) participates in several signaling pathways. This membrane phospholipid controls the Akt (protein kinase B) phosphorylation process.

包裝

5 mL Clear Glass Sealed Ampule (840030P-10mg)
5 mL Clear Glass Sealed Ampule (840030P-25mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

儲存類別代碼

11 - Combustible Solids


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Akt-GSK3 beta Pro-survival Signaling Pathway in Cerebral Ischemic Injury
Primer on Kidney Diseases, Volume 953, 269-272 (2017)
Analysis of complex lipidomes
Medical Applications of Mass Spectrometry, 223-249 (2008)
Carolina Varela Chavez et al.
Cellular microbiology, 17(10), 1477-1493 (2015-04-18)
Clostridium sordellii lethal toxin (TcsL) is a potent virulence factor belonging to the large clostridial glucosylating toxin family. TcsL enters target cells via receptor-mediated endocytosis and delivers the N-terminal catalytic domain (TcsL-cat) into the cytosol upon an autoproteolytic process. TcsL-cat
Chi L L Pham et al.
Bioscience reports, 33(5) (2013-09-27)
The deposition of α-syn (α-synuclein) as amyloid fibrils and the selective loss of DA (dopamine) containing neurons in the substantia nigra are two key features of PD (Parkinson's disease). α-syn is a natively unfolded protein and adopts an α-helical conformation
Peter A Leventis et al.
Annual review of biophysics, 39, 407-427 (2010-03-03)
Phosphatidylserine (PS) is the most abundant negatively charged phospholipid in eukaryotic membranes. PS directs the binding of proteins that bear C2 or gamma-carboxyglutamic domains and contributes to the electrostatic association of polycationic ligands with cellular membranes. Rather than being evenly

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