810603P

16:0-10 Doxyl PC

Avanti Research^™ - A Croda Brand 810603P, powder

• 同義詞: 1-palmitoyl-2-stearoyl-(10-doxyl)-sn-glycero-3-phosphocholine
• 經驗公式（希爾表示法）: C₄₆H₉₀N₂O₁₀P
• CAS號碼: 188004-25-3
• 分子量：: 862.19
• 分類程式碼代碼: 41141825
• NACRES: NA.25

屬性

• 化驗: >99% (TLC)
• 形狀: powder
• 包裝: pkg of 1 × 1 mg (810603P-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand 810603P
• 脂質類型: ESR probes; phospholipids
• 運輸包裝: dry ice
• 儲存溫度: −20°C

描述

一般說明

Avanti′s nitroxide spin product listing is a group of compounds designed to act as membrane probes. A variety of positions down the hydrophobic chain are labeled with the nitroxide functional groups to allow probing the membrane at various depths. These compounds have been synthesized from 1-palmitoyl-2-hydroxy-sn-glycerol-3-phosphocholine with the product being purified by column chromatography. Various n-doxyl phosphocholines have been recently used as biophysical tools to elucidate membrane trafficking with phosphatidylinositol transfer proteins and as fluorescent quenchers in lipid bilayer structural studies.

Phosphocholine is considered as a precursor molecule. It is formed during the breakdown of phosphatidylcholine metabolism. 10-Doxyl is a spin label probe.

應用

16:0-10 Doxyl PC may be used:

• in vesicles for quenching PT-(1–46)F4W fluorescence
• as vesicle component for tryptophan based fluorescence emission studies
• to probe the oxygen and Ni[II] ethylenediaminediacetic acid (NiEdda) accessibilities inside liposomes

生化／生理作用

Phosphatidylcholine (PC) functions as a surfactant within the mucus to form a hydrophobic surface to inhibit bacterial penetrance.

包裝

5 mL Clear Glass Sealed Ampule (810603P-1mg)

準備報告

Product use: To prevent aggregation, prepare water-based solutions of 2 mM stock solutions of n-DOXYL PCs and store in plastic. Dilute stock solutions to 0.03- 0.1 mM solutions for EPR studies. For liposome preparations in fluorescent quenching measurements, dissolve the doxyl lipid in 150 μl absolute ethanol for a concentration of 40.3 mM , Additional supplemental information.

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids