810280P
Avanti
TopFluor™ Lyso PA
Avanti Research™ - A Croda Brand 810280P, powder
同義詞:
1-{12-[4-(dipyrrometheneboron difluoride)butanoyl]amino}dodecanoyl-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)
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About This Item
經驗公式（希爾表示法）:
C32H54BF2N4O8P
CAS號碼:
分子量：:
702.57
MDL號碼:
分類程式碼代碼:
12352211
NACRES:
NA.25
推薦產品
化驗
>99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
形狀
powder
包裝
pkg of 1 × 1 mg (810280P-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810280P
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
Lysophosphatidic acid (LPA) is a water-soluble, bioactive phospholipid. It is seen in mammalian cells and tissues, including blood. LPA is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells.
應用
TopFluor™ Lyso PA may be used as the chromophore and as a component in the formation of the Langmuir-Blodgett (LB) film.
生化／生理作用
Lysophosphatidic acid (LPA) is very essential in signaling. It may alter proliferation, survival, cytoskeletal changes and calcium influx. It plays a key role in neointimal formation, endothelium dysfunction, monocyte attraction and adhesion.
包裝
5 mL Amber Glass Screw Cap Vial (810280P-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
儲存類別代碼
11 - Combustible Solids
Lysophosphatidic acid triggers apoptosis in HeLa cells through the upregulation of tumor necrosis factor receptor superfamily member 21
Dong Y, et al.
Mediators of Inflammation (2017)
Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21
Dong Y, et al.
Mediators of Inflammation (2017)
Diffusional motion as a gauge of fluidity and interfacial adhesion. Supported alkylphosphonate monolayers
Baumler SM, et al.
Journal of Colloid and Interface Science, 468, 145-155 (2016)
Lysophosphatidic acid (LPA) receptors: signaling properties and disease relevance
Lin ME, et al.
Prostaglandins & other lipid mediators, 91(3-4), 130-138 (2010)
Lauren P Saunders et al.
The Journal of biological chemistry, 286(34), 30130-30141 (2011-07-02)
Autotaxin (ATX) is a secreted lysophospholipase D that hydrolyzes lysophosphatidylcholine (LPC) into lysophosphatidic acid (LPA), initiating signaling cascades leading to cancer metastasis, wound healing, and angiogenesis. Knowledge of the pathway and kinetics of LPA synthesis by ATX is critical for
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