推薦產品
化驗
>99% (TLC)
形狀
liquid
包裝
pkg of 1 × 1 mL (810155C-1mg)
製造商／商標名
Avanti Research™ - A Croda Brand 810155C
濃度
1 mg/mL (810155C-1mg)
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) is a fluorescent probe where the fluorescent NBD label is attached to the headgroup of phosphatidylethanolamine. The NBD moiety is known to localize to the membrane interface. Phosphoethanolamine is the second most abundant andmetabolically related aminophospholipid. It is mostly enriched in brain.
應用
18:1-06:0 NBD PE has been used as a liposomal supplement for protein reconstitution into liposomes and scrambling experiments. It may also be used to analyse the temporal fluorescent pattern of Chol-E-NBD.
生化／生理作用
N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) phosphoethanolamine (NBD PE) plays a vital role as a fluorescent probe in the studies of organization and dynamics of membranes. Phosphoethanolamine (PE) acts as a substrate for several phospholipids of the cell membrane.
包裝
5 mL Amber Glass Screw Cap Vial (810155C-1mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
水污染物質分類（WGK）
WGK 3
Formation and function of phosphatidylserine and phosphatidylethanolamine in mammalian cells
Vance JE and Tasseva G
The FEBS journal, 37-50 (2012)
Fluorescent methods to study biological membranes, 37-50 (2012)
Synthetic phosphoethanolamine induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells through the mitochondrial pathway
Ferreira AK, et al.
Biomedicine and Pharmacotherapy, 37-50 (2012)
Bieong-Kil Kim et al.
Bioorganic & medicinal chemistry letters, 25(18), 3893-3896 (2015-08-06)
Cholesterol-based fluorescent lipids with ether linker were synthesized using NBD (Chol-E-NBD) or Rhodamine B (Chol-E-Rh), and the usefulnesses as fluorescent probes for tracing cholesterol-based liposomes were validated. The fluorescent intensities of liposomes containing these modified lipids were measured and observed
Cardiolipin and phosphatidylethanolamine role in dibucaine interaction with the mitochondrial membrane
Lopes SC, et al.
Biochimica et biophysica acta. General subjects, 37-50 (2012)
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