710332C
Avanti
14:0 Cardiolipin (ammonium salt)
1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt), chloroform
同義詞:
1,1′,2,2′-tetramyristoyl cardiolipin (ammonium salt); 1,1′,2,2′-tetratetradecanoyl cardiolipin (ammonium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])
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About This Item
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![14:0 Cardiolipin (sodium salt) 1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt), chloroform](/deepweb/assets/sigmaaldrich/product/images/390/523/992bed4e-3608-4209-aa6e-fa9206a4a31b/640/992bed4e-3608-4209-aa6e-fa9206a4a31b.jpg)
化驗
>99% (TLC)
形狀
solution
包裝
pkg of 1 × 2.5 mL (710332C-25mg)
製造商／商標名
Avanti Research™ - A Croda Brand 710332C
濃度
10 mg/mL (710332C-25mg)
脂質類型
phospholipids
cardiolipins
運輸包裝
dry ice
儲存溫度
−20°C
一般說明
14:0 Cardiolipin is an acidic phospholipid. Structurally, cardiolipin comprises three glycerol moieties and four acyl chains and is localized in the inner membrane of mitochondria. 14:0 Cardiolipin contains four myristic acid as acyl chain.
應用
14:0 Cardiolipin (1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (ammonium salt)) has been used:
- as a standard in tandem mass spectrometry
- in the preparation of membrane proximal region (MPR) of human immunodeficiency virus (HIV-1) glycoprotein 41 (gp41)-lipopeptide conjugate and liposomes
- as a component of micelle for suspending C8 ceramide substrate in ceramide kinase assay
生化／生理作用
Cardiolipin (CL) plays a key role in oxidative phosphorylation. CL is essential for energy production and in the activation of apoptosis. Deficiency of CL is associated with the development of diabetes and age-related heart failure. Anomalies associated with CL composition is observed in Barth Syndrome (BTHS).
包裝
5 mL Clear Glass Sealed Ampule (710332C-25mg)
法律資訊
Avanti Research is a trademark of Avanti Polar Lipids, LLC
訊號詞
Danger
危險分類
Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
標靶器官
Central nervous system, Liver,Kidney
水污染物質分類（WGK）
WGK 3
分析證明 (COA)
輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。
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The journal of physical chemistry. B, 117(42), 12878-12886 (2013-05-30)
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