700024P

7α,27-dihydroxycholesterol

Avanti Research^™ - A Croda Brand

• 同義詞: 111116
• 經驗公式（希爾表示法）: C₂₇H₄₆O₃
• CAS號碼: 4725-24-0
• 分子量：: 418.65
• MDL號碼: MFCD22416719
• 分類程式碼代碼: 12352211
• NACRES: NA.25

屬性

• 形狀: powder
• 包裝: pkg of 1 × 1 mg (700024P-1mg)
• 製造商／商標名: Avanti Research^™ - A Croda Brand
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• SMILES 字串: O[C@H]1[C@H]2[C@H]3[C@@]([C@H](CC3)[C@@H](CCCC(CO)C)C)(CC[C@@H]2[C@]4(CC[C@@H](CC4=C1)O)C)C
• InChI: 1S/C27H46O3/c1-17(16-28)6-5-7-18(2)21-8-9-22-25-23(11-13-27(21,22)4)26(3)12-10-20(29)14-19(26)15-24(25)30/h15,17-18,20-25,28-30H,5-14,16H2,1-4H3/t17?,18-,20+,21-,22+,23+,24-,25+,26+,27-/m1/s1
• InChI 密鑰: RXMHNAKZMGJANZ-DTTSCKGMSA-N

描述

一般說明

7α,27-dihydroxycholesterol (7α,27-di-OHC) is an oxysterol with oxidized side chains. 7α,27-dihydroxycholesterol (7α27-OHC) is synthesized by the hydroxylation of 27-Hydroxycholesterol (27-OHC) and is a structural isomer of 7α,25-dihydroxycholesterol (7α25-OHC).

生化／生理作用

7α,27-dihydroxycholesterol (7α,27-di-OHC) is one of the metabolite screened in pathological conditions such as neurological diseases, Smith-Lemli-Opitz syndrome, obesity metabolic syndrome and diabetes by lipidomics analysis of human specimens. Upon the lipopolysaccharide activation, the levels of 7α,27-di-OHC decreases.7α27-OHC is a ligand for Epstein-Barr virus-induced gene 2 (EBI2).

包裝

5 mL Amber Glass Screw Cap Vial (700024P-1mg)

法律資訊

Avanti Research is a trademark of Avanti Polar Lipids, LLC

安全資訊

• 儲存類別代碼: 11 - Combustible Solids