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Key Documents

W352316

Sigma-Aldrich

四氢吡咯

FG

同義詞:

吡咯烷, 甲氢氮杂茂

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About This Item

經驗公式(希爾表示法):
C4H9N
CAS號碼:
分子量::
71.12
FEMA號碼:
3523
Beilstein:
102395
EC號碼:
MDL號碼:
分類程式碼代碼:
12164502
PubChem物質ID:
Flavis號碼:
14.064
NACRES:
NA.21

生物源

synthetic

等級

FG
Halal

agency

meets purity specifications of JECFA

法律遵循

EU Regulation 1334/2008 & 178/2002

蒸汽密度

2.45 (vs air)

蒸汽壓力

128 mmHg ( 39 °C)
49 mmHg ( 20 °C)

自燃溫度

653 °F

expl. lim.

10.6 %

折射率

n20/D 1.443 (lit.)

密度

0.852 g/mL at 25 °C (lit.)

應用

flavors and fragrances

文件

see Safety & Documentation for available documents

食物過敏原

no known allergens

感官的

fishy

SMILES 字串

C1CCNC1

InChI

1S/C4H9N/c1-2-4-5-3-1/h5H,1-4H2

InChI 密鑰

RWRDLPDLKQPQOW-UHFFFAOYSA-N

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訊號詞

Danger

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A

儲存類別代碼

3 - Flammable liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

37.4 °F - closed cup

閃點(°C)

3 °C - closed cup

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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分析證明 (COA)

Lot/Batch Number

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Pieter Van der Veken et al.
Journal of medicinal chemistry, 55(22), 9856-9867 (2012-11-06)
We have investigated the effect of regiospecifically introducing substituents in the P2 part of the typical dipeptide derived basic structure of PREP inhibitors. This hitherto unexplored modification type can be used to improve target affinity, selectivity, and physicochemical parameters in
Adele Faulkner et al.
Chemical communications (Cambridge, England), 49(15), 1521-1523 (2013-01-17)
We report efficient Pd-catalyzed cyclizations of oxime esters with 1,1-disubstituted alkenes as the basis of a general entry to α,α-disubstituted pyrrolidine derivatives. We also demonstrate that catalytic asymmetric variants of this chemistry are feasible by employing a suitable chiral ligand.
Joseph T Paletta et al.
Organic letters, 14(20), 5322-5325 (2012-10-12)
A series of sterically shielded pyrrolidine nitroxides were synthesized, and their reduction by ascorbate (vitamin C) indicate that nitroxide 3, a tetraethyl derivative of 3-carboxy-PROXYL, is reduced at the slowest rate among known nitroxides, i.e., at a 60-fold slower rate
Y Arun et al.
Bioorganic & medicinal chemistry letters, 23(6), 1839-1845 (2013-02-12)
Novel dispirooxindole-pyrrolidine derivatives have been synthesized through 1,3-dipolar cycloaddition of an azomethine ylide generated from isatin and sarcosine with the dipolarophile 3-(1H-indol-3-yl)-3-oxo-2-(2-oxoindolin-3-ylidene)propanenitrile, and also spiro compound of acenaphthenequinone obtained by the same optimized reaction condition. Synthesized compounds were evaluated for
Hiroaki Chiba et al.
Angewandte Chemie (International ed. in English), 51(36), 9169-9172 (2012-08-15)
In control: The novel and enantioselective total synthesis of (-)-quinocarcin includes the highly stereoselective preparation of the 2,5-cis-pyrrolidine by intramolecular amination, a selective substrate-controlled 6-endo-dig intramolecular alkyne hydroamination with a cationic Au(I) catalyst, and Lewis-acid-mediated ring-opening/halogenation sequence.

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