QBD11471

MAL-dPEG^®₁₂-Tris(m-dPEG^®₂₄)₃

>95% (HPLC)

• 同義詞: Branched Maleimide-PEG-m, Branched mPEG-maleimide, MAL-NH-PEG₆₀₀-Tris(mPEG₁₀₀₀)₃, MAL-PEG₁₂-Tris(m-PEG₂₄)₃
• 經驗公式（希爾表示法）: C₁₉₄H₃₇₈N₆O₉₄
• 分子量：: 4299.06
• 分類程式碼代碼: 12352106
• NACRES: NA.22

屬性

• 化驗: >95% (HPLC)
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Pegylations
• 聚合物結構: functionality: monofunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

特點和優勢

MAL-dPEG₁₂-Tris(m-dPEG₂₄)₃ is a thiol-reactive, methyl-terminated, four-arm monodispersed PEG product designed to modulate biodistribution of conjugates. Tris forms the core of the molecule. Three equal-length methyl-terminated long arms plus one maleimido-terminated short arm extend from the tris core. From the maleimido olefin to the terminal methyl groups on each arm, the end-to-end length of this product is 127 atoms with an average distance of 103.7 Å. The amphiphilic PEG imparts hydrophilicity to conjugates, reduces or eliminates the conjugates′ antigenicity, and increases the hydrodynamic volume of conjugated molecules. Applications for this product include eradicating renal clearance, maintaining in vivo circulation for more extended periods, and suppressing immune responses to conjugates.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable