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Merck
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Key Documents

QBD10866

Sigma-Aldrich

SPDP-dPEG®36-acid

>95% (HPLC)

同義詞:

OPSS-PEG1500-acid, OPSS-PEG36-acid, SPDP-PEG-acid, SPDP-PEG36-COOH, SPDP-PEG36-acid

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About This Item

經驗公式(希爾表示法):
C83H158N2O39S2
分子量::
1872.26
MDL號碼:
分類程式碼代碼:
12352106
NACRES:
NA.22

化驗

>95% (HPLC)

形狀

solid or viscous liquid

反應適用性

reaction type: Pegylations

聚合物結構

shape: linear
functionality: heterobifunctional

運輸包裝

ambient

儲存溫度

−20°C

特點和優勢

SPDP-dPEG36-acid is a crosslinking reagent designed to conjugate free amines and sulfhydryls. The single molecular weight (i.e., monodispersed) PEG crossbridge between the two functional groups is 115 atoms (137.8 Å) long. Using a suitable carbodiimide, such as EDC, the propionic acid group reacts with free primary amines to form amide bonds. The pyridyl disulfide (SPDP, also known as OPSS) functional group reacts with free thiols to form disulfide bonds. This product is useful for crosslinking peptides, proteins, and small molecules, and modifying surfaces with suitable reactive sites. SPDP-dPEG36-acid is a monodisperse equivalent of the polymeric PEG1500.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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