QBD10850

Thiol-dPEG^®₁₂-acid

>95% (HPLC)

• 同義詞: CT(PEG)₁₂, Carboxy-PEG-Thiol, Carboxy-PEG₁₂-Thiol, HS-PEG₁₂-COOH, Thiol-PEG₁₂-acid
• 經驗公式（希爾表示法）: C₂₇H₅₄O₁₄S
• 分子量：: 634.77
• MDL號碼: MFCD21363238
• 分類程式碼代碼: 12162002
• NACRES: NA.22

屬性

• 化驗: >95% (HPLC)
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Pegylations
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C

描述

特點和優勢

Thiol-dPEG₁₂-acid is a single molecular weight, discrete-length polyethylene glycol (dPEG) crosslinking PEGylation reagent. One end of the crosslinker terminates in a sulfhydryl (thiol) group. Propionic acid terminates the opposite end. The thiol end of the molecule forms dative bonds with gold. Moreover, it forms thioether bonds with maleimide and bromoacetate groups and disulfide bonds with other sulfhydryl groups. The propionic acid group reacts with amines to form amide bonds. Alternatively, if it is left unreacted, the propionic acid group provides a negative charge to the conjugated molecule or modified surface. The monodispersed dPEG spacer is 39 atoms (46.8 Å) long.

法律資訊

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable