QBD10774

NHS-dPEG^®₂₄-biotin

• 同義詞: Polyethylene glycol
• 經驗公式（希爾表示法）: C₆₅H₁₂₀N₄O₃₀S
• 分子量：: 1469.72
• 分類程式碼代碼: 51171641
• PubChem物質ID: 329823948
• NACRES: NA.22

屬性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: Biotinylations; reactivity: amine reactive; reagent type: cross-linking reagent
• 聚合物結構: shape: linear; functionality: monofunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O=C(CCCCC1SCC(N2)C1NC2=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O

描述

一般說明

NHS-dPEG^®₂₄-biotin is a cross-linking reagent used in biotinylation reactions. The N-hydroxysuccinimidyl (NHS) moiety of NHS-dPEG^®₂₄-biotin forms a stable amide bond with free primary amines, such as the amines on the side chain of lysine. The biotin moiety is used in a variety of applications, including labeling, supramolecular building, affinity chromatography, pull-down assays, and the production of biotinylated antibodies.

特點和優勢

NHS-dPEG^®₂₄-biotin is used extensively to label molecules that contain a free amine with biotin. The single molecular weight NHS-dPEG^®₂₄-biotin compound has a long spacer of precise length (97.7 Å) between the biotin moiety and the labeled molecule. This dPEG^® spacer imparts a high degree of water solubility to the biotin label. For biotinylated peptides and proteins, the dPEG^® spacer dramatically reduces aggregation and precipitation of the modified molecule and reduces non-specific binding of the molecule, both of which are common problems with molecules that have been biotinylated with the widely used NHS-LC-biotin.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable