QBD10513

Azido-dPEG^®₁₂-acid

• 同義詞: Polyethylene glycol, alpha-(2-azidoethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl)
• 經驗公式（希爾表示法）: C₂₇H₅₃N₃O₁₄
• CAS號碼: 1167575-20-3
• 分子量：: 643.72
• MDL號碼: MFCD21363301
• 分類程式碼代碼: 12352106
• PubChem物質ID: 329823935
• NACRES: NA.22

屬性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reaction type: click chemistry; reagent type: cross-linking reagent; reaction type: click chemistry
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])=O

描述

特點和優勢

The azido-dPEG^®₁₂ contains an azide function on one end of a single molecular weight dPEG^® spacer (46.4 Å) and a reactive group on the other end of the spacer. The dPEG^® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. The reactive acid functional group may be activated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) or N,N′-dicyclohexylcarbodiimide (DCC) for conjugation to an amine. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable