QBD10203

TFP-dPEG^®₄-biotinidase resistant biotin

• 經驗公式（希爾表示法）: C₃₁H₄₄F₄N₄O₉S
• 分子量：: 724.76
• 分類程式碼代碼: 51171641
• PubChem物質ID: 329823892
• NACRES: NA.22

屬性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reagent type: cross-linking reagent; reaction type: Biotinylations; reactivity: amine reactive; reagent type: linker
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: O=C1NC(C2N1)CSC2CCCCC(NC(C(NCCOCCOCCOCCOCCC(OC3=C(C(F)=CC(F)=C3F)F)=O)=O)CC)=O
• InChI: 1S/C31H44F4N4O9S/c1-2-21(37-24(40)6-4-3-5-23-28-22(18-49-23)38-31(43)39-28)30(42)36-8-10-45-12-14-47-16-15-46-13-11-44-9-7-25(41)48-29-26(34)19(32)17-20(33)27(29)35/h17,21-23,28H,2-16,18H2,1H3,(H,36,42)(H,37,40)(H2,38,39,43)
• InChI 密鑰: IOOKENPHEAMTTM-UHFFFAOYSA-N

描述

特點和優勢

TFP-dPEG^®₄-biotinidase resistant biotin contains an amine reactive TFP ester and chemically modified biotin that is stable in the presence of biotinidase. Resistance to biotinidase cleavage of biotin is necessary in some biotechnology applications. The chemical modification to biotin imparts resistance to biotinidase cleavage without reducing the strength of biotin-avidin binding. The single molecular weight dPEG^® spacer imparts water solubility, prevents aggregation and precipitation of labeled peptides and proteins, and reduces non-specific binding. Two different single molecular weight dPEG^® spacers are available for precise spatial control between the modified biotin and the surface of the molecule to which it is conjugated.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable