QBD10119

Acid-dPEG^®₉-NHS ester

• 同義詞: Polyethylene glycol
• 經驗公式（希爾表示法）: C₂₆H₄₅NO₁₅
• 分子量：: 611.63
• MDL號碼: MFCD28064339
• 分類程式碼代碼: 12352106
• PubChem物質ID: 329823880
• NACRES: NA.22

屬性

• 化驗: >90%
• 形狀: solid or viscous liquid
• 反應適用性: reagent type: cross-linking reagent; reactivity: amine reactive
• 官能基: NHS ester; carboxylic acid
• 聚合物結構: shape: linear; functionality: heterobifunctional
• 運輸包裝: ambient
• 儲存溫度: −20°C
• SMILES 字串: OC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(ON1C(CCC1=O)=O)=O)=O

描述

特點和優勢

Acid-dPEG^®₉-NHS ester is a unique heterobifunctional dPEG^® crosslinking product which allows conjugation to two different moieties, each containing free amines. Because the single molecular weight dPEG^® spacers contain an N-hydroxysuccinimide ester only on one end of the spacer, greater control of the conjugation reaction can be maintained. The free acid end of the spacer can be left unreacted to modify the surface properties of the molecule to which it is conjugated, or the free acid end can be activated and conjugated to a different group at a later time. The dPEG^® spacers provide precise spacing/distance control, and the dPEG^® itself provides the well-known benefits of increased water solubility; decreased immunogenicity; protection from proteolysis; increased hydrodynamic volume; and increased serum half-life.

法律資訊

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable