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Merck
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重要文件

N21804

Sigma-Aldrich

3-硝基苯肼 盐酸盐

98%

同義詞:

1-(3-硝基苯基)肼盐酸盐, 3-硝基苯肼单盐酸盐, 3-硝基苯肼盐酸盐, 间硝基苯肼盐酸盐

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About This Item

線性公式:
O2NC6H4NHNH2 · HCl
CAS號碼:
分子量::
189.60
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.22

化驗

98%

形狀

powder

mp

210 °C (dec.) (lit.)

SMILES 字串

Cl.NNc1cccc(c1)[N+]([O-])=O

InChI

1S/C6H7N3O2.ClH/c7-8-5-2-1-3-6(4-5)9(10)11;/h1-4,8H,7H2;1H

InChI 密鑰

BKOYKMLGFFASBG-UHFFFAOYSA-N

一般說明

3-Nitrophenylhydrazine (3-NPH) is a derivatizing reagent used for the derivatization of carboxyl- and carbonyl-containing metabolites. This compound is also used as a high-efficiency chemical isotope-labeling reagent. Additionally, 3-nitrophenylhydrazine undergoes a condensation reaction with substituted benzaldehydes resulting in the formation of a series of ten substituted (E)-1-benzylidene-2-(3-nitrophenyl) hydrazine compounds.

應用

<ul>
<li><strong>分析化学中的衍生化剂:</strong>利用LC-MRM-MS技术,将3-硝基苯基肼盐酸盐用作衍生化剂,用于检测感染单纯疱疹病毒1型的生物样品中的γ -羟基丁酸,从而增强法医和临床毒理学的检测能力(Osinaga等人,2022)。</li>
<li><strong>药物配方中的残留分析:</strong>该化合物还可用于氯霉素及其制剂中残留的4-硝基苯甲醛的定量分析,采用3-硝基苯肼衍生化后的高效液相色谱-紫外/可见检测,为保证药品的纯度和安全性提供了可靠的方法(Luo et al., 2018)。</li>
<li><strong>法医在分解分析中的应用:</strong>用于衍生化法医尸检时采集的血液样本(Matoba et al., 2022)。</li>
</ul>

象形圖

Exclamation mark

訊號詞

Warning

危險分類

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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