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Merck
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重要文件

G8503

Sigma-Aldrich

18α-甘草次酸

≥95%

同義詞:

18α-甘草次酸, 18-异甘草次酸, 3β-Hydroxy-11-oxo-18α,20β-olean-12-en-29-oic acid

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About This Item

經驗公式(希爾表示法):
C30H46O4
CAS號碼:
分子量::
470.68
EC號碼:
MDL號碼:
分類程式碼代碼:
12352115
PubChem物質ID:
NACRES:
NA.22

品質等級

化驗

≥95%

SMILES 字串

[H][C@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)C4[C@@]5(C)CC[C@H](O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O

InChI

1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21+,22+,23-,26-,27+,28+,29-,30-/m1/s1

InChI 密鑰

MPDGHEJMBKOTSU-PMTKVOBESA-N

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一般說明

18α-甘草次酸 (18α-GA) 是一种在甘草中发现的具有生物活性的三萜类化合物。其显示对 11-HSD1(11-羟基类固醇脱氢酶 1)的选择性抑制。其对肝星状细胞 (HSC) 也有抗增殖和凋亡作用。

應用

18α-甘草次酸可用于合成:
  • 3-酮-18α-甘草次酸
  • 18α-甘草次酸甲酯
  • 3-酮基-18α-甘草次酸甲酯

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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