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重要文件

CBR00329

Sigma-Aldrich

4-Hydrazinoquinazoline

AldrichCPR

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About This Item

經驗公式(希爾表示法):
C8H8N4
CAS號碼:
分子量::
160.18
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:

形狀

solid

SMILES 字串

NNC1=NC=NC2=CC=CC=C12

InChI

1S/C8H8N4/c9-12-8-6-3-1-2-4-7(6)10-5-11-8/h1-5H,9H2,(H,10,11,12)

InChI 密鑰

QVKNQXCOGYNFPC-UHFFFAOYSA-N

其他說明

Please note that Sigma-Aldrich provides this product to early discovery researchers as part of a collection of unique chemicals. Sigma-Aldrich does not collect analytical data for this product. Buyer assumes responsibility to confirm product identity and/or purity. All sales are final.

NOTWITHSTANDING ANY CONTRARY PROVISION CONTAINED IN SIGMA-ALDRICH′S STANDARD TERMS AND CONDITIONS OF SALE OR AN AGREEMENT BETWEEN SIGMA-ALDRICH AND BUYER, SIGMA-ALDRICH SELLS THIS PRODUCT "AS-IS" AND MAKES NO REPRESENTATION OR WARRANTY WHATSOEVER WITH RESPECT TO THIS PRODUCT, INCLUDING ANY (A) WARRANTY OF MERCHANTABILITY; (B) WARRANTY OF FITNESS FOR A PARTICULAR PURPOSE; OR (C) WARRANTY AGAINST INFRINGEMENT OF INTELLECTUAL PROPERTY RIGHTS OF A THIRD PARTY; WHETHER ARISING BY LAW, COURSE OF DEALING, COURSE OF PERFORMANCE, USAGE OF TRADE OR OTHERWISE.

法律資訊

Product of ChemBridge Corp.

象形圖

Skull and crossbonesCorrosion

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Eye Dam. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Kazuhiro Yamazaki et al.
Journal of enzyme inhibition and medicinal chemistry, 28(1), 143-147 (2011-12-16)
Poly(ADP-ribose) polymerase (PARP)-1 inhibitor has been suggested to attenuate the ischemia-reperfusion injury. We investigated the protective effect of the cardioplegia with a PARP-1 inhibitor, 4-hydoxyquinazoline (4-HQ), against myocardial ischemia-reperfusion injury. Isolated rat hearts were perfused on a Langendorff apparatus and
Andriy G Golub et al.
European journal of medicinal chemistry, 58, 258-264 (2012-11-07)
Hepatitis C virus (HCV) NS5B polymerase is a key target for the development of anti-HCV drugs. Here we report on the identification of novel allosteric inhibitors of HCV NS5B through a combination of structure-based virtual screening and in vitro NS5B
Maher A El-Hashash et al.
Global journal of health science, 4(1), 174-183 (2012-09-18)
The reactions of 2-ethoxy-4-hydrazinoquinazoline 2 with diethyl oxalate and ethyl chloroacetate gave 6-ethoxy-2H-[1,2,4]triazino[4,3-c]quinazoline-3,4-dione 3 and 6-ethoxy-2,3-dihydro-4H-[1,2,4]triazino[4,3-c]quinazolin-4-one 4 respectively. A series of 5-ethoxy-2-X-[1,2,4]triazolo[1, 5-c]quinazolines 5a-d was also produced by reacting 2 with the acid chlorides namely: benzoyl, crotonyl, cinnamyl and 2-furoyl
V V Dunaev et al.
Ukrainskii biokhimicheskii zhurnal (1978), 65(3), 118-120 (1993-05-01)
It is established that KS-79 compound possesses the high level of antioxidant activity and realizes its antioxidant effect at initial stages of free-radical hydrogen peroxide oxidation of lipids. Due to this ability it differs from the oxidants of direct-type action.
[Hemato-encephalic barrier function in strokes in patients with arterial hypertension under drug correction].
V V Dunaev et al.
Likars'ka sprava, (5-6)(5-6), 124-126 (1995-05-01)

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