推薦產品
品質等級
化驗
99%
形狀
powder or crystals
光學活性
[α]20/D −42°, c = 2 in ethanol
反應適用性
reaction type: solution phase peptide synthesis
技術
NMR: suitable
顏色
white
mp
76-78 °C (lit.)
應用
peptide synthesis
SMILES 字串
OC(=O)[C@@H]1CCCN1C(=O)OCc2ccccc2
InChI
1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1
InChI 密鑰
JXGVXCZADZNAMJ-NSHDSACASA-N
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應用
Z-Pro-OH can be used:
- As a starting material to prepare aib-pro endothiopeptides of pharmacological importance.
- To prepare biologically significant fluorophore-labeled peptide tetramers or dimers.
- As a reactant to synthesize benzoxazole derived human neutrophil elastase (HNE) inhibitors.
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
A new dendrimer scaffold for preparing dimers or tetramers of biologically active molecules
Tetrahedron Letters, 46(9), 1463-1465 (2005)
Design and synthesis of peptide-based carboxylic acid-containing transition-state inhibitors of human neutrophil elastase
Bioorganic & medicinal chemistry letters, 12(4), 551-555 (2002)
Cytotoxicity of carbobenzoxy-protected amino acids.
In vitro cellular & developmental biology : journal of the Tissue Culture Association, 28A(5), 300-302 (1992-05-01)
Biochimica et biophysica acta, 1744(2), 157-163 (2005-05-10)
Prolidase deficiency (PD) is a recessive disorder of the connective tissue caused by mutations in the prolidase, a specific peptidase, cleaving the dipeptides with a C-terminal prolyl and hydroxyprolyl residue. PD is a complex syndrome characterized mainly by intractable skin
European journal of pharmacology, 649(1-3), 115-119 (2010-09-28)
Transforming growth factor beta 1 (TGF β1) is a protein that in most cells control proliferation and differentiation. One of the best characterized functions of TGF β1 is stimulation of collagen biosynthesis that may lead to tissue fibrosis. Several reports
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