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934631

Sigma-Aldrich

Microneedle loader set

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About This Item

分類程式碼代碼:
44111809

一般說明

Microneedles are a platform for transdermal drug delivery. The advantages of microneedles include the delivery of large molecules, painless and less invasive administration of the active pharmaceutical ingredient (API), ease of administration, and improved drug delivery including dose, delivery rate and efficacy. Microneedles are also effective for vaccine delivery due to the abundance of immune cells in the dermis.

The microneedle loader set can be used with the microneedle applicator set and microneedle templates to make and apply reproducible and high quality microneedle patches for a variety of therapeutics.

應用

Transdermal delivery of a variety to therapeutics including:
  • Nucleic acid delivery
  • Vaccine delivery
  • Protein or peptide delivery
  • Small molecule delivery

特點和優勢

The microneedle loader set are to be used with the microneedle applicator set for applying microneedle patches on the skin.

物理性質

Each set comes with:
  • 10 buttons
  • 10 loaders
  • 10 caps
Product specifications:
  • Dimensions: 21.5mm diameter x 43mm length
  • Loadable patch area: Max. diameter 11mm
  • Biocompatible: Yes
  • Autoclavable: Yes

其他說明

Suggested instructions for use when used with the Microneedle applicator set :

1. Affix a microneedle patch on the surface of the button.
2. Push the button into the loader with the microneedles facing inward and the keys facing outward.
3. To load the button onto the bolt of the applicator, hold the loader and align its kits to fit into the holes of the bolt.
4. Push the loader and bolt to cock the applicator, and turn the loader 90 degrees to lock the button into the bolt.
5. Remove the loader to expose the microneedle patch. Applicator is ready to use.

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Jie Xu et al.
Molecules (Basel, Switzerland), 26(19), 5912-5912 (2021-10-14)
A microneedle (MN) is a painless and minimally invasive drug delivery device initially developed in 1976. As microneedle technology evolves, microneedles with different shapes (cone and pyramid) and forms (solid, drug-coated, hollow, dissolvable and hydrogel-based microneedles) have been developed. The

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