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Merck
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Key Documents

934119

Sigma-Aldrich

Ovine collagen

SPDP functionalized, low endotoxin

同義詞:

CollOvine-SPDP

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About This Item

CAS號碼:
分類程式碼代碼:
12352202
NACRES:
NA.28

品質等級

形狀

lyophilized

雜質

Bioburden, none detected
≤0.1 EU/mg Endotoxin

顏色

white to off-white

官能基

SPDP

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一般說明

Collagen is a major component of the extracellular matrix (ECM) and offers low immunogenicity, a porous structure, good permeability, and biocompatibility to promote cell viability, adhesion, spreading, proliferation and differentiation.

Low endotoxin SPDP functionalized collagen derived from ovine can be used for the covalent conjugation with sulfhydryl-containing molecules. The primary amine groups (lysine residues) of the collagen are reacted with succinimidyl 3-(2-pyridyldithio)propionate (SPDP) to yield collagen derived with a cleavable disulfide bond. The cleaved linker can react with other species containing containing free sulhydryl groups (i.e. cysteine residues) which are commonly found in many naturally occurring protein or peptide sequences.

應用

  • 3D bioprinting
  • Tissue engineering
  • Drug delivery
  • Regenerative medicine
  • Cell culture, encapsulation, expansion and differentiation

特點和優勢

  • Certified Disease Free Sheep
  • 93-97% Type I Collagen
  • 3-7% Type III Collagen
  • 99% Purity
  • Prion Free

法律資訊

CollOvine is a trademark of OviGenex LLC

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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